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Penis

  • Steven S. Shen
  • Luan D. Truong
  • Jae Y. Ro
Chapter
Part of the Frozen Section Library book series (FROZEN, volume 2)

Abstract

The two main indications for intraoperative FS for penile cancer are margin evaluation for partial or total penectomies and nodal status evaluation. It has been shown that the use of intraoperative FS can lead to a concomitant decrease in both positive surgical margins and recurrence in squamous cell carcinoma or Paget’s disease.76, 77 Nowadays, the diagnosis of penile cancer is made almost exclusively by tissue biopsy before definitive surgery. In fact, using FS for the purpose of diagnosis at the time of surgery is discouraged because it is often difficult or impossible to make a distinction between a well-differentiated squamous cell carcinoma or verucous carcinoma from nonneoplastic conditions.

Keywords

Squamous Cell Carcinoma Corpus Cavernosa Penile Cancer Cytologic Atypia Verrucous Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 76.
    Hoffman MA, Renshaw AA, Loughlin KR. Squamous cell carcinoma of the penis and microscopic pathologic margins: how much margin is needed for local cure? Cancer. 1999;85:1565–1568.CrossRefPubMedGoogle Scholar
  2. 77.
    Zhu Y, Ye DW, Chen ZW, Zhang SL, Qin XJ. Frozen section-guided wide local excision in the treatment of penoscrotal extramammary Paget’s disease. BJU Int. 2007;100:1282–1287.CrossRefPubMedGoogle Scholar
  3. 78.
    Ornellas AA, Seixas AL, de Moraes JR. Analyses of 200 lymphadenectomies in patients with penile carcinoma. J Urol. 1991;146:330–332.PubMedGoogle Scholar
  4. 79.
    Abi-Aad AS, deKernion JB. Controversies in ilioinguinal lymphadenectomy for cancer of the penis. Urol Clin North Am. 1992;19:319–324.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Steven S. Shen
    • 1
    • 2
  • Luan D. Truong
    • 1
    • 2
    • 3
  • Jae Y. Ro
    • 1
    • 2
  1. 1.Weill Medical College of Cornell University New YorkNew YorkUSA
  2. 2.The Methodist HospitalHoustonUSA
  3. 3.Baylor College of MedicineHoustonUSA

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