Fish Oil and Importance of Its Ingredients in Human Diet

  • Akhlaq A. Farooqui

Interest in the potential health benefits of fish oil increased immensely after epidemiological studies indicated a remarkably low incidence of death from ischemic heart disease in Greenland Eskimos, despite their consumption of a high-fat and cholesterol-enriched diet (Bang et al., 1976). Low incidences of ischemic heart disease have also been reported in coastal-dwelling Turkish and Japanese populations consuming fish and fish constituent-enriched diet. Soon it became apparent that fatty fish and marine oils, which were major components of the Eskimo, coastal Turkish, and Japanese diets, were responsible for the low incidence of ischemic heart disease (Kagawa et al., 1982). These studies are supported by hard data from several prevential studies such as GISSI Prevenzione, JELIS, DART, and RCT Trials, which indicated the usefulness of fish oil for the treatment of heart disease in patients (GISSI-Prevenzione investigators, 1999; Yokoyama et al., 2007; Burr et al., 1989; Nilsen et al., 2001; Bucher et al., 2002; Studer et al., 2005).


Oleic Acid Sudden Cardiac Death Trans Fatty Acid Mediterranean Diet Human Aortic Endothelial Cell 
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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of Molecular and Cellular BiochemistryThe Ohio State UniversityColumbusUSA

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