The Epidemiology of Testicular Cancer

Part of the Cancer Genetics book series (CANGENETICS)


Testicular cancer is a rare tumor among the general population, but is the most common type of cancer among young men in many countries. The vast majority of testicular cancers are germ cell tumors. As a result, the terms “testicular cancer” and “testicular germ cell tumors” (TGCT) are often used interchangeably. Globally, the incidence of TGCT is highest among men of northern European ancestry and lowest among men of Asian and African descent. Incidence rates of TGCT have been increasing around the world for at least 50 years, but mortality rates, at least in developed countries, have been declining. While reasons for the decreases in mortality are related to improvements in therapeutic regimes introduced in the late 1970s, reasons for the increase in incidence are less well understood. An accumulating body of evidence suggests, however, that TGCT arises in fetal life. As the great majority of TGCTs arise among men between the ages of 15 and 44 years, this chapter will focus on the etiology of the tumors in this age group.


Testicular Cancer Testicular Germ Cell Tumor Sibship Size Testicular Microlithiasis Kallmann Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and GeneticsNational Cancer Institute, NIH, DHHSBethesdaUSA

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