Eyelid malposition in cancer patients encompasses a variety of conditions, including ectropion, entropion, ptosis, eyelid retraction, and eyelid malposition due to periorbital edema. Ectropion is by far the most commonly encountered form of eyelid malposition in cancer patients. In some situations, the eyelid abnormality is the presenting sign of an underlying malignancy, but most often, it is the result of therapeutic interventions for cancer.
Mahoney NR, Liu GT, Menacker SJ, et al. Pediatric Horner syndrome: etiologies and roles of imaging and urine studies to detect neuroblastoma and other responsible mass lesions. Am J Ophthalmol 2006;142:651–9.PubMedCrossRefGoogle Scholar
van Oosterom AT, Judson I, Verweij J, et al. European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 2001;358:1421–3.PubMedCrossRefGoogle Scholar
Esmaeli B, Prieto VG, Butler CE, et al. Severe periorbital edema secondary to STI571 (Gleevec). Cancer 2002;95:881–7.PubMedCrossRefGoogle Scholar
Larson JS, Bergstrom LK, Cameron JD, et al. Severe periorbital edema secondary to imatinib mesylate for chronic myelogenous leukemia. Arch Ophthalmol 2007;125:985–6.PubMedCrossRefGoogle Scholar