Abstract
Chronic pain has a substantial adverse impact on the health-related quality of life of children and adolescents, resulting in significantly worse physical functioning, psychological functioning, social functioning, lower satisfaction with life, and poorer self-perceived health status (Merlijn et al. 2006; Palermo 2000; Palermo et al. 2008). The current Pediatric Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (PedIMMPACT) has accordingly recommended that investigators conducting pediatric clinical trials in chronic and recurrent pain consider assessing not only pain intensity but also physical function, emotional function, role function, other condition-related symptoms and adverse events, global judgment of satisfaction with treatment, sleep, and economic factors (www.immpact.org) (McGrath et al. 2008).
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Vetter, T.R. (2011). The Epidemiology of Pediatric Chronic Pain. In: McClain, B., Suresh, S. (eds) Handbook of Pediatric Chronic Pain. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0350-1_1
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