The Role of Physical Therapy and Occupational Therapy in the Rehabilitation of Pediatric and Adolescent Patients with Osteosarcoma

Part of the Cancer Treatment and Research book series (CTAR, volume 152)


The approach to rehabilitation of patients with osteosarcoma has evolved with the many advances in the medical treatment and surgical management of this pediatric and adolescent cancer. In the past, amputation (often radical amputation) was the standard method for treating patients with extremity sarcomas, and rehabilitation was geared toward providing either functional training for patients who had not had limb replacement or prosthetic training for those who had received prostheses. Currently, limb-sparing procedures combined with adjuvant chemotherapy (and occasionally radiotherapy) are used to treat most patients with this disease. In addition, physical-therapy and occupational-therapy interventions are now tailored to address the multiple physical and psychosocial difficulties these patients will face for the remainder of their lives. Integral parts of the interdisciplinary team, practitioners of these disciplines, provide services that enable patients to achieve their highest functional status to permit them to return to their role in society and hence enjoy dignity and improved quality of life.


Occupational Therapist Rehabilitation Process Physical Therapist Occupational Therapy Assistive Device 
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  1. 1.
    Lane JM, Christ GH, Khan SN, et al. Rehabilitation for limb salvage patients: kinesiologic parameters and psychological assessment. Cancer. 2001;92(4 Suppl):1013–1019.CrossRefPubMedGoogle Scholar
  2. 2.
    Campanacci MC. Classic osteosarcoma. In: Campanacci MC, ed. Bone and Soft Tissue Tumors. Vienna: Springer-Verlag; 1990:455–505.Google Scholar
  3. 3.
    Tunn P-U, Schmidt-Peter P, Pomraenke D, et al. Osteosarcoma in children: long-term functional analysis. Clin Orthop. 2004;421:212–217.CrossRefPubMedGoogle Scholar
  4. 4.
    Ginsberg J, Rai S, Carlson C, Meadows A 2007. A comparative analysis of functional outcomes in adolescents and young adults with lower-extremity bone sarcoma. Pediatr Blood Cancer. 2007;49:964–969.CrossRefPubMedGoogle Scholar
  5. 5.
    Longhi A, Errani C, De Paolis M, et al. Tumor review: primary bone osteosarcoma in the pediatric age: state of the art. Cancer Treat Rev. 2006; 32(6):423–426.CrossRefPubMedGoogle Scholar
  6. 6.
    Hopyan S, Tan J, Graham K, et al. Function and upright time following limb salvage, amputation, and rotationplasty for pediatric sarcoma of bone. J Pediatr Orthop. 2006;26:405–408.PubMedGoogle Scholar
  7. 7.
    American Physical Therapy Association. Information for consumers. <>; 2007 Retrieved 15.05.2007
  8. 8.
    Yadav R. Rehabilitation of surgical cancer patients at University of Texas M.D. Anderson Cancer Center. J Surg Oncol. 2007;95:361–369.CrossRefPubMedGoogle Scholar
  9. 9.
    Leavitt LA. Rehabilitation problems of the cancer patient. Rehabilitation of the Cancer Patient: A Collection of Papers presented at the 15th Annual Clinical Conference on Cancer; 1970, at the University of Texas M.D. Anderson Hospital and Tumor Institute, at Houston, Texas. Chicago, IL: Year Book Medical Publishers, Inc; 1972:49–55.Google Scholar
  10. 10.
    Cheville A. Rehabilitation of patients with advanced cancer. Cancer. 2001;92(suppl 4):1039–1048.CrossRefPubMedGoogle Scholar
  11. 11.
    Brown A, Parsons J, Martino C. Work status after distal femoral Kotz reconstruction for malignant tumors of bone. Arch Phys Med Rehabil. 2003;84:62–68.CrossRefPubMedGoogle Scholar
  12. 12.
    Gudas S. Rehabilitation of pediatric and adult sarcomas. Rehabil Oncol. 2000;18(3):10–13.Google Scholar
  13. 13.
    Refaat, Y., Gunnoe, J., Hornicek, F et al. Comparison of quality of life after amputation or limb salvage. Clin Orthop Relat Res. 2002;397:298–305.CrossRefPubMedGoogle Scholar
  14. 14.
    Ness, K., Mersten, A., Hudson, M., Wall, M et al. Limitations on physical performance and daily activities among long-term survivors of childhood cancer. Ann Intern Med. 2005;143:639–647.PubMedGoogle Scholar
  15. 15.
    Marchese, V., Spearing, E., Callaway, L et al. Relationships among range of motion, functional mobility, and quality of life in children and adolescents after limb-sparing surgery for lower-extremity sarcoma. Pediatr Phys Ther. 2006;18(4):238–244.CrossRefPubMedGoogle Scholar
  16. 16.
    Pakulis, PJ., Young, N., Davis, A. Review: evaluating physical function in an adolescent bone tumor population. Pediatr Blood Cancer. 2005;45:635–643.CrossRefPubMedGoogle Scholar
  17. 17.
    Lewis V. (2005). Limb salvage in the skeletally immature patient. Curr Oncol Rep Curr Sci. 1523–3790, 287–292.Google Scholar
  18. 18.
    Tsauo JY, Li WC, Yang RS. Functional outcomes after endoprosthetic knee reconstruction following resection of osteosarcoma near the knee. Disabil Rehabil. 2006;28(1):61–66.CrossRefPubMedGoogle Scholar
  19. 19.
    Benedetti, MG, Catani, F, Donati, D, et al. Muscle performance about the knee joint in patients who had distal femoral replacement after resection of a bone tumor: an objective study with gait analysis. J Bone Joint Surg. 2000;82-A(11):1619–1625.PubMedGoogle Scholar
  20. 20.
    Porr SM, Rainville EB. Pediatric Therapy: A Systems Approach. Philadelphia, PA: FA Davis Company; 1999.Google Scholar
  21. 21.
    Penfold S. The role of occupational therapist in oncology. Cancer Treat Rev. 1996;22:75–81.CrossRefPubMedGoogle Scholar
  22. 22.
    Cooper J, ed. Occupational Therapy in Oncology and Palliative Care. London: Whurt Publishers Ltd; 2003.Google Scholar
  23. 23.
    Shin KY, Gillis TA, Fine SM. Cancer Rehabilitation: General Principles in Physical Medicine and Rehabilitation Secrets. Philadelphia, PA: Hanley & Belfus, Inc.; 2002; VII:55.Google Scholar
  24. 24.
    Griffith E. (1981) Rehabilitation of children with bone and soft tissue sarcomas: a physiatrist’s viewpoint. Natl Cancer Inst Monogr. 36, 137–143.Google Scholar
  25. 25.
    Lenhard RE Jr, Osten RT, Gansler T. Clinical Oncology. Atlanta, GA: American Cancer Society; 2001.Google Scholar
  26. 26.
    Yasko A, Reece G, Gillis T, Pollock R. Limb-salvage strategies to optimize quality of life: the M.D. Anderson Cancer Center Experience. CA Cancer J Clin. 1997;47:226–238.CrossRefPubMedGoogle Scholar
  27. 27.
    Varricchio CG, ed. Ades TB, Hinds PS, Pierce M, assoc eds. A Cancer Source Book for Nurses, 8th ed. Sudbury, MA: Jones & Bartlett Publishers; 2004.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Rehabilitation Services DepartmentMD Anderson Cancer CenterHoustonUSA

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