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The Absorption Barrier

  • Gerrit BorchardEmail author
Chapter

Abstract

This chapter attempts to give an overview on the properties of the intestinal epithelium with regard to both, barriers to transcellular (transporter and efflux systems) and paracellular (tight junctional complex) drug absorption and transport systems and tight junction modulation. A short introduction into the relation between the innate immune system and modulation of paracellular permeability is equally given.

Keywords

Tight Junction Intestinal Epithelium Breast Cancer Resistance Protein Trefoil Family Factor Tight Junctional Complex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Laboratory of Pharmaceutics and Biopharmaceutics, School of Pharmaceutical SciencesUniversity of GenevaGenevaSwitzerland

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