Strategies in Oral Immunization

  • Pavla Simerska
  • Peter Moyle
  • Colleen Olive
  • Istvan Toth


Development of mucosal vaccine delivery system is an important area for improving public health. Oral vaccines have large implications for rural and remote populations since the access to trained medical staff to administer vaccines by injection is limited. New mucosal vaccine strategies are focused on development of non-replicating subunit vaccines, DNA, plant, and other types of recombinant vaccines. The conjugation of lipids to peptide antigens is one approach which enables the production of highly customized all-in-one self-adjuvanting vaccines. Lipid-modified peptide vaccines have been successfully investigated in humans and demonstrated to be potent and more importantly very safe.


Oral Vaccine Mucosal Vaccine Lipoamino Acid Live Vector Vaccine Lipidated Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Pavla Simerska
    • 1
  • Peter Moyle
    • 1
  • Colleen Olive
    • 1
  • Istvan Toth
    • 1
  1. 1.School of Chemistry & Molecular Biosciences, School of PharmacyUniversity of QueenslandBrisbaneAustralia

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