Pharmacology of the Pulmonary Circulation

  • Cara Reimer
  • John Granton


The pulmonary vasculature is a complex system and studies of the effects of anesthetic drugs on this system are often contradictory. A balanced anesthetic technique with adherence to the hemodynamic goals of maintenance of right ventricular preload and right coronary perfusion is the safest choice for patients with PHTN. There are no absolute contraindications to most anesthetic drugs in patients with pulmonary hypertension. Inhaled pulmonary vasodilators can be used to optimize hemodynamic variables perioperatively, although effects on gas exchange are variable.


Nitric Oxide Interstitial Lung Disease Lung Transplantation Pulmonary Artery Pressure Anesthetic Drug 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Cardiac output


(Mean) pulmonary artery pressure


Pulmonary hypertension


Paravertebral block


Pulmonary vascular resistance (index)


Systemic vascular resistance (index)


Thoracic epidural analgesia


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Cara Reimer
    • 1
  • John Granton
    • 2
  1. 1.Department of Anesthesiology and Perioperative MedicineKingston General HospitalKingstonCanada
  2. 2.Division of Respirology, Department of MedicineUniversity of Toronto and University Health Network, Mount Sinai Hospital, Women’s College HospitalTorontoCanada

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