Physiology of the Lateral Decubitus Position, Open Chest and One-Lung Ventilation

  • Jens Lohser
  • Seiji Ishikawa


Ventilation and perfusion matching is optimized for gas exchange. Induction of anesthesia, one-lung ventilation (OLV) and opening of the chest progressively uncouple ventilation–perfusion (V/Q) matching. Hypoxic pulmonary vasoconstriction (HPV) improves V/Q matching during OLV, but can be impaired by anesthetic interventions.


Cardiac Output Pulmonary Blood Flow Lateral Decubitus Position Hypoxic Pulmonary Vasoconstriction Shunt Flow 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Jens Lohser
    • 1
  • Seiji Ishikawa
    • 2
  1. 1.Department of Anesthesiology, Pharmacology, and TherapeuticsUniversity of British Columbia, Vancouver General HospitalVancouverCanada
  2. 2.Department of AnesthesiologyTokyo Medical and Dental University, Graduate School of Medical and Dental SciencesTokyoJapan

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