Skip to main content

Thoracic Anesthesia for Morbidly Obese Patients and Obese Patients with Obstructive Sleep Apnea

  • Chapter
  • First Online:

Abstract

Body mass index (BMI) (BMI  =  Weightkilograms/(Height) 2meters ) is a measure of obesity. A patient with a BMI >30 kg/m2 is obese, and >40 kg/m2 morbidly obese (MO). Morbid obesity is associated with medical conditions including hypertension, type II diabetes, cardiac disease, and obstructive sleep apnea (OSA). Moderate to severe OSA is present in more than 50% of MO patients, and is often unrecognized. Definitive diagnosis is made by polysomnography (PSG). In the absence of PSG documentation, all MO patients should be managed as if they have OSA. The ASA Practice Guidelines for the Perioperative Management of Patients with Obstructive Sleep Apnea should be used for all MO patients, whether or not they have had a PSG diagnosis of OSA. The best preoperative predictors of potential problems with tracheal intubation in MO patients are high Mallampati (III or IV) score and increased neck circumference (>48 cm men, >40 cm women). Many MO are difficult to ventilate by face mask, but the majority have no difficulty undergoing direct laryngoscopy and tracheal intubation. Never allow a supine MO patient to breathe without assistance. A MO patient should be positioned in the head-elevated laryngoscopy position (HELP) prior to anesthetic induction. In this position, the patient’s head and upper body are ramped or “stacked” so that an imaginary horizontal line can be drawn from the sternum to the ear. If the patient is hemodynamically stable, the operating room table should also be in a reverse-Trendelenburg position (RTP) to maximize “safe apnea time.” MO patients tolerate one-lung ventilation (OLV) in the lateral position. Although there are no clinical studies of OLV in supine MO patients, in theory a MO patient would not be expected to tolerate OLV this position. A MO OSA patient using a continuous positive airway pressure (CPAP) device preoperatively should bring their equipment to the hospital for use during their postoperative recovery. Depressant medications can decrease ventilatory responsiveness to hypoxemia and hypercarbia in all MO patients, and can also cause airway collapse in OSA patients. Avoid sedative premedication and long-lasting opioids since both increase the risk of postoperative ventilatory problems. Use regional techniques when possible. For postoperative analgesia, use multimodal analgesic therapy (local anesthetics for epidural, spinal and paravertebral analgesia, nonsteroidal anti-inflammatory agents, and alpha-2 agonists (clonidine, dexmedetomidine)) to reduce the need for opioids. Following any long-duration operation check the patient’s serum for creatinine phosphokinase (CPK). A CPK level >1,000 IU/L is diagnostic for rhabdomyolysis (RML). The initial symptoms of RML (numbness, pain, weakness) can be masked, especially if epidural analgesia is being used.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Lohser J, Kulkarni V, Brodsky JB. Anesthesia for thoracic surgery in morbidly obese patients. Curr Opin Anaesthesiol. 2007;20:10–4.

    Article  PubMed  Google Scholar 

  2. Baskin ML, Ard J, Franklin F, et al. Prevalence of obesity in the United States. Obes Rev. 2005;6:5–7.

    Article  PubMed  CAS  Google Scholar 

  3. Lemmens HJ, Brodsky JB, Bernstein DP. Estimating ideal body weight – a new formula. Obes Surg. 2005;15:1082–3.

    Article  PubMed  Google Scholar 

  4. Davis G, Patel JA, Gagne DJ. Pulmonary considerations in obesity and the bariatric surgical patient. Med Clin N Am. 2007;91:433–42.

    Article  PubMed  Google Scholar 

  5. Stierer T, Punjabi NM. Demographics and diagnosis of obstructive sleep apnea. Anesthesiol Clin N Am. 2005;23:405–20.

    Article  Google Scholar 

  6. Koenig SM. Pulmonary complications of obesity. Am J Med Sci. 2001;321:249–79.

    Article  PubMed  CAS  Google Scholar 

  7. Crummy F, Piper AJ, Naughton MT. Obesity and the lung: 2 Obesity and sleep- disordered breathing. Thorax. 2008;63:738–46.

    Article  PubMed  CAS  Google Scholar 

  8. Mokhlesi B, Tulaimat A. Recent Advances in obesity hypoventilation syndrome. Chest. 2007;132:1322–36.

    Article  PubMed  Google Scholar 

  9. Schumann R, Jones SB, Ortiz VE, et al. Best practice recommendations for anesthetic perioperative care and pain management in weight loss surgery. Obes Res. 2005;13:254–66.

    Article  PubMed  Google Scholar 

  10. Brodsky JB, Lemmens HJ, Brock-Utne JG, et al. Morbid obesity and tracheal intubation. Anesth Analg. 2002;94:732–6.

    Article  PubMed  Google Scholar 

  11. Pelosi P, Croci M, Ravagnan I, et al. The effects of body mass on lung volumes, respiratory mechanics, and gas exchange during general anesthesia. Anesth Analg. 1998;87:654–60.

    PubMed  CAS  Google Scholar 

  12. Licker MJ, Widikker I, Robert J, et al. Operative mortality and respiratory complications after lung resection for cancer: impact of chronic obstructive pulmonary disease and time trends. Ann Thorac Surg. 2006;81:1830–7.

    Article  PubMed  Google Scholar 

  13. von Ungern-Sternberg BS, Regli A, et al. Effect of obesity and thoracic epidural analgesia on perioperative spirometry. Br J Anaesth. 2005;94:121–7.

    Article  Google Scholar 

  14. Alpert MA, Fraley MA, Birchem JA, et al. Management of obesity cardiomyopathy. Expert Rev Cardiovasc Ther. 2005;3:225–30.

    Article  PubMed  Google Scholar 

  15. Sidana J, Aronow WS, Ravipati G, et al. Prevalence of moderate or severe left ventricular diastolic dysfunction in obese persons with obstructive sleep apnea. Cardiology. 2005;104:107–9.

    Article  PubMed  Google Scholar 

  16. Kaw R, Michota F, Jaffer A, et al. Unrecognized sleep apnea in the surgical patient: implications for the perioperative setting. Chest. 2006;129:198–205.

    Article  PubMed  Google Scholar 

  17. Pashayan AG, Passannante AN, Rock P. Pathophysiology of obstructive sleep apnea. Anesthesiol Clin N Am. 2005;23:431–43.

    Article  Google Scholar 

  18. Chung F, Yegneswaran B, Liao P, et al. Validation of the Berlin questionnaire and the American Society of Anesthesiologists checklist as screening tools for obstructive sleep apnea in surgical patients. Anesthesiology. 2008;108:822–30.

    Article  PubMed  Google Scholar 

  19. Chung F, Yegneswaran B, Liao P, et al. STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology. 2008;108:812–21.

    Article  PubMed  Google Scholar 

  20. Gross JB, Bachenberg KL, Benumof JL, et al. Practice guidelines for the perioperative management of patients with obstructive sleep apnea. Anesthesiology. 2006;104:1081–93.

    Article  PubMed  Google Scholar 

  21. Couch EM, Senior B. Nonsurgical and surgical treatments for sleep apnea. Anesthesiol Clin N Am. 2005;23:525–34.

    Article  Google Scholar 

  22. Mokhlesi B, Kryger MH, Grunstein RR. Assessment and management of patients with obesity hypoventilation syndrome. Proc Am Thorac Soc. 2008;5:218–25.

    Article  PubMed  Google Scholar 

  23. Altermatt FR, Muñoz HR, Delfino AE, et al. Pre-oxygenation in the obese patient: effects of position on tolerance to apnoea. Br J Anaesth. 2005;95:706–9.

    Article  PubMed  CAS  Google Scholar 

  24. Collins JS, Lemmens HJ, Brodsky JB, et al. Laryngoscopy and morbid obesity: a comparison of the “sniff” and “ramped” positions. Obes Surg. 2004;14:1171–5.

    Article  PubMed  Google Scholar 

  25. Perilli V. Determinants of improvement in oxygenation consequent to reverse Tredelenburg position in anesthetized morbidly obese patients. Obes Surg. 2004;14:866–7.

    Article  PubMed  CAS  Google Scholar 

  26. Dixon BJ, Dixon JB, Carden JR, et al. Preoxygenation is more effective in the 25 degrees head-up position than in the supine position in severely obese patients: a randomized controlled study. Anesthesiology. 2005;102:1110–5.

    Article  PubMed  Google Scholar 

  27. Boyce JR, Ness T, Castroman P, et al. A preliminary study of the optimal anesthesia positioning for the morbidly obese patient. Obes Surg. 2003;13:4–9.

    Article  PubMed  Google Scholar 

  28. Brunette KE, Hutchinson DO, Ismail H. Bilateral brachial ­plexopathy following laparoscopic bariatric surgery. Anaesth Intensive Care. 2005;33:812–5.

    PubMed  CAS  Google Scholar 

  29. Ingrande J, Brodsky JB, Lemmens HJM. Weight-based dosing scalars for the anesthetic induction dose of propofol in morbidly obese subjects. Anesth Analg. 2010 Sept 22 [Epub ahead of publication]

    Google Scholar 

  30. Lemmens HJ, Brodsky JB. The dose of succinylcholine in morbid obesity. Anesth Analg. 2006;102:438–42.

    Article  PubMed  CAS  Google Scholar 

  31. Arain SR, Barth CD, Shankar H, et al. Choice of volatile anesthetic for the morbidly obese patient: sevoflurane or desflurane. J Clin Anesth. 2005;17:413–9.

    Article  PubMed  CAS  Google Scholar 

  32. Brodsky JB, Lemmens HJ, Saidman LJ. Obesity, surgery, and inhalation anesthetics – is there a “drug of choice”? Obes Surg. 2006;16:734.

    Article  PubMed  Google Scholar 

  33. Practice guidelines for management of the difficult airway. an updated report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway. Anesthesiology. 2003;98:1269–77.

    Article  Google Scholar 

  34. Kheterpal S, Han R, Tremper KK, et al. Incidence and predictors of difficult and impossible mask ventilation. Anesthesiology. 2006;105:885–91.

    Article  PubMed  Google Scholar 

  35. Collins JS, Lemmens HJ, Brodsky JB. Obesity and difficult intubation: where is the evidence? Anesthesiology. 2006;104:617.

    Article  PubMed  Google Scholar 

  36. Benumof JL. Obesity, sleep apnea, the airway and anesthesia. Curr Opin Anaesthesiol. 2004;17:21–30.

    Article  PubMed  Google Scholar 

  37. Keller C, Brimacombe J, Kleinsasser A, et al. The Laryngeal Mask Airway ProSeal™ as a temporary ventilatory device in grossly and morbidly obese patients before laryngoscope-guided tracheal intubation. Anesth Analg. 2002;94:737–40.

    Article  PubMed  Google Scholar 

  38. Ezri T, Gewurtz G, Sessler DI, et al. Prediction of difficult laryngoscopy in obese patients by ultrasound quantification of anterior neck soft tissue. Anaesthesia. 2003;58:1111–4.

    Article  PubMed  CAS  Google Scholar 

  39. Gonzalez H, Minville V, Delanoue K, et al. The importance of increased neck circumference to intubation difficulties in obese patients. Anesth Analg. 2008;106:1132–6.

    Article  PubMed  Google Scholar 

  40. Jean J, Compère V, Fourdrinier V, et al. The risk of pulmonary aspiration in patients after weight loss due to bariatric surgery. Anesth Analg. 2008;107:1257–9.

    Article  PubMed  Google Scholar 

  41. Combes X, Sauvat S, Leroux B, et al. Intubating laryngeal mask airway in morbidly obese and lean patients: a comparative study. Anesthesiology. 2005;102:1106–9.

    Article  PubMed  Google Scholar 

  42. Dhonneur G, Ndoko SK, Yavchitz A, et al. Tracheal intubation of morbidly obese patients: LMA CTrach vs direct laryngoscopy. Br J Anaesth. 2006;97:742–5.

    Article  PubMed  CAS  Google Scholar 

  43. Shulman MS, Brodsky JB, Levesque PR. Fibreoptic bronchoscopy for tracheal and endobronchial intubation with a double-lumen tube. Can J Anaesth. 1987;34:172–3.

    Article  PubMed  CAS  Google Scholar 

  44. Brodsky JB, Lemmens HJ. Tracheal width and left double-lumen tube size: a formula to estimate left-bronchial width. J Clin Anesth. 2005;17:267–70.

    Article  PubMed  Google Scholar 

  45. Slinger PD, Lesiuk L. Flow resistances of disposable double-lumen, single-lumen, and Univent tubes. J Cardiothorac Vasc Anesth. 1998;12:142–4.

    Article  PubMed  CAS  Google Scholar 

  46. Brodsky JB, Wyner J, Ehrenwerth J, et al. One-lung anesthesia in morbidly obese patients. Anesthesiology. 1982;57:132–4.

    Article  PubMed  CAS  Google Scholar 

  47. Bardoczky GI, Szegedi LL, d’Hollander AA, et al. Two-lung and one-lung ventilation in patients with chronic obstructive pulmonary disease: the effects of position and F(IO)2. Anesth Analg. 2000;90:35–41.

    Google Scholar 

  48. Watanabe S, Noguchi E, Yamada S, et al. Sequential changes of arterial oxygen tension in the supine position during one-lung ventilation. Anesth Analg. 2000;90:28–34.

    Article  PubMed  CAS  Google Scholar 

  49. Henzler D, Rossaint R, Kuhlen R. Is there a need for a ­recruiting strategy in morbidly obese patients undergoing laparoscopic surgery? Anesth Analg. 2004;98:268.

    Article  PubMed  Google Scholar 

  50. Lohser J. Evidence-based management of one-lung ventilation. Anesthesiol Clin. 2008;26:241–72.

    Article  PubMed  Google Scholar 

  51. Bardoczky GI, Yernault JC, Houben JJ, et al. Large tidal volume ventilation does not improve oxygenation in morbidly obese patients during anesthesia. Anesth Analg. 1995;81:385–8.

    PubMed  CAS  Google Scholar 

  52. Senturk NM, Dilek A, Camci E, et al. Effects of positive end-expiratory pressure on ventilatory and oxygenation parameters during pressure-controlled one-lung ventilation. J Cardiothorac Vasc Anesth. 2005;19:71–5.

    Article  PubMed  Google Scholar 

  53. Michelet P, Roch A, Brousse D, et al. Effects of PEEP on oxygenation and respiratory mechanics during one-lung ventilation. Br J Anesth. 2005;95:267–73.

    Article  CAS  Google Scholar 

  54. Frey WC, Pilcher J. Obstructive sleep-related breathing disorders in patients evaluated for bariatric surgery. Obes Surg. 2003;13:676–83.

    Article  PubMed  Google Scholar 

  55. Gaszynski T, Tokarz A, Piotrowski D, et al. Boussignac CPAP in the postoperative period in morbidly obese patients. Obes Surg. 2007;17:452–6.

    Article  PubMed  Google Scholar 

  56. Neligan PJ, Malhotra G, Fraser M, et al. Continuous positive airway pressure via the Boussignac system immediately after extubation improves lung function in morbidly obese patients with obstructive sleep apnea undergoing laparoscopic bariatric surgery. Anesthesiology. 2009;110:878–84.

    Article  PubMed  Google Scholar 

  57. Maniscalco M, Zedda A, Faraone S, et al. Evaluation of a transcutaneous carbon dioxide monitor in severe obesity. Intensive Care Med. 2008;34:1340–4.

    Article  PubMed  Google Scholar 

  58. Slinger PD. Perioperative fluid management for thoracic surgery: the puzzle of postpneumonectomy pulmonary edema. J Cardiothorac Vasc Anesth. 1995;9:442–51.

    Article  PubMed  CAS  Google Scholar 

  59. Lemmens HJ, Bernstein DP, Brodsky JB. Estimating blood volume in obese and morbidly obese patients. Obes Surg. 2006;16:773–6.

    Article  PubMed  Google Scholar 

  60. Wu CL, Cohen SR, Richman JM, et al. Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids. A meta-analysis. Anesthesiology. 2005;103:1079–88.

    Article  PubMed  CAS  Google Scholar 

  61. Davies RG, Myles PS, Graham JM. A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy – a systematic review and meta-analysis of ­randomized trials. Br J Anaesth. 2006;96:418–26.

    Article  PubMed  CAS  Google Scholar 

  62. Wahlander S, Frumento RJ, Wagener G, et al. A prospective, double-blind, randomized, placebo-controlled study of dexmedetomidine as an adjunct to epidural analgesia after thoracic surgery. J Cardiothorac Vasc Anesth. 2005;19:630–5.

    Article  PubMed  CAS  Google Scholar 

  63. Hofer RE, Sprung J, Sarr MG, et al. Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics. Can J Anaesth. 2005;52:176–80.

    Article  PubMed  Google Scholar 

  64. Wigfield CH, Lindsey JD, Munoz A, et al. Is extreme obesity a risk factor for cardiac surgery? An analysis of patients with a BMI > or = 40. Eur J Cardiothorac Surg. 2006;9:34–40.

    Google Scholar 

  65. Wagner BD, Grunwald GK, Rumsfeld JS, et al. Relationship of body mass index with outcomes after coronary artery bypass graft surgery. Ann Thorac Surg. 2007;84:10–6.

    Article  PubMed  Google Scholar 

  66. Tyson 3rd GH, Rodriguez E, Elci OC, et al. Cardiac procedures in patients with a body mass index exceeding 45: outcomes and long-term results. Ann Thorac Surg. 2007;84:3–9.

    Article  PubMed  Google Scholar 

  67. Smith PW, Wang H, Gazoni LM, et al. Obesity does not increase complications after anatomic resection for non-small cell lung cancer. Ann Thorac Surg. 2007;84:1098–105.

    Article  PubMed  Google Scholar 

  68. Chataigner O, Fadel E, Yildizeli B, et al. Factors affecting early and long-term outcomes after completion pneumonectomy. Eur J Cardiothorac Surg. 2008;33:837–43.

    Article  PubMed  Google Scholar 

  69. Suemitsu R, Sakoguchi T, Morikawa K, et al. Effect of body mass index on perioperative complications in thoracic surgery. Asian Cardiovasc Thorac Ann. 2008;16:463–7.

    PubMed  Google Scholar 

  70. Mullen JT, Davenport DL, Hutter MM, et al. Impact of body mass index on perioperative outcomes in patients undergoing major intra-abdominal cancer surgery. Ann Surg Oncol. 2008;15:2164–72.

    Article  PubMed  Google Scholar 

  71. Eichenberger A, Proietti S, Wicky S, et al. Morbid obesity and postoperative pulmonary atelectasis: an underestimated problem. Anesth Analg. 2002;95:1788–92.

    Article  PubMed  Google Scholar 

  72. Flier S, Knape JT. How to inform a morbidly obese patient on the specific risk to develop postoperative pulmonary complications using evidence-based methodology. Eur J Anaesthesiol. 2006;2:154–9.

    Article  Google Scholar 

  73. Davenport DL, Xenos ES, Hosokawa P, et al. The influence of body mass index obesity status on vascular surgery 30-day morbidity and mortality. J Vasc Surg. 2009;49:140–7.

    Article  PubMed  Google Scholar 

  74. Dindo D, Muller MK, Weber M, et al. Obesity in general elective surgery. Lancet. 2003;361:2032–5.

    Article  PubMed  Google Scholar 

  75. de Menezes Ettinger JE, dos Santos Filho PV, Azaro E, Melo CA, et al. Prevention of rhabdomyolysis in bariatric surgery. Obes Surg. 2005;15:874–9.

    Article  PubMed  Google Scholar 

  76. Kong SS, Ho ST, Huang GS, et al. Rhabdomyolysis after a long-term thoracic surgery in right decubitus position. Acta Anaesthesiol Sin. 2000;38:223–8.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jay B. Brodsky MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Brodsky, J.B. (2011). Thoracic Anesthesia for Morbidly Obese Patients and Obese Patients with Obstructive Sleep Apnea. In: Slinger, MD, FRCPC, P. (eds) Principles and Practice of Anesthesia for Thoracic Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0184-2_26

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-0184-2_26

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0183-5

  • Online ISBN: 978-1-4419-0184-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics