Chemical Imaging: Magnetic Resonance Spectroscopy: The Basics
Magnetic Resonance Spectroscopy enables the detection and quantification of a wide range of cerebral metabolite compounds in vivo. Proton (1H) magnetic resonance spectroscopy in particular holds great potential for characterizing the pathophysiology of disease states and may provide important biomarkers particularly at the level of inhibitory and excitatory amino acid neurotransmitter systems. However, the field of in vivo magnetic resonance spectroscopy contains a multitude of concepts that may be unfamiliar to many readers. The present chapter is an overview of the basic fundamentals of proton magnetic resonance spectroscopy data acquisition and post processing strategies, which are currently are employed by investigators worldwide for characterizing the metabolic profile of the central nervous system and its associated disease states.
KeywordsMagnetic Resonance Spectroscopy Magnetic Resonance Spectroscopic Imaging Amino Acid Neurotransmitter Central Nervous System Drug Magnetic Resonance Spectroscopy Data
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