Regulation and Control of Metabolism

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


Metabolism involves not just single biochemical reactions, but coordinated networks of reactions. These networks are usually remarkably well-regulated, keeping close to a set-point, a steady-state or dynamic equilibrium in most healthy organisms. Substantial deviation from that set-point may betoken disease or some other extraordinary circumstance. On the other hand, biotechnologists may want to manipulate an organism to overproduce a desirable product, controlling its metabolism to deviate from the normal set-point. Groen and Westerhoff [30] have listed four questions that theories of metabolic control should answer


Metabolic Network Forward Rate Phase Plot Flux Control Linear Pathway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag New York 2009

Authors and Affiliations

  1. 1.Department of Biochemistry, Molecular Biology, and BiophysicsUniversity of Minnesota6-155 Jackson Hall MinneapolisUSA

Personalised recommendations