Regulation and Control of Metabolism

Chapter
Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Abstract

Metabolism involves not just single biochemical reactions, but coordinated networks of reactions. These networks are usually remarkably well-regulated, keeping close to a set-point, a steady-state or dynamic equilibrium in most healthy organisms. Substantial deviation from that set-point may betoken disease or some other extraordinary circumstance. On the other hand, biotechnologists may want to manipulate an organism to overproduce a desirable product, controlling its metabolism to deviate from the normal set-point. Groen and Westerhoff [30] have listed four questions that theories of metabolic control should answer

Keywords

Oligomerization NADH Rium 

Copyright information

© Springer-Verlag New York 2009

Authors and Affiliations

  1. 1.Department of Biochemistry, Molecular Biology, and BiophysicsUniversity of Minnesota6-155 Jackson Hall MinneapolisUSA

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