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Effect of Tunisian Plant Extract on Melanogenesis

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Book cover Animal Cell Technology: Basic & Applied Aspects

Part of the book series: Animal Cell Technology: Basic & Applied Aspects ((ANICELLTECH,volume 15))

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Abstract

In this study, we determined whether Tunisian aromatic plants can induce melanogenesis in the cultured mouse melanoma cell line, B16. The cells were cultured with or without Tunisian aromatic plant extracts. We found that melanogenesis was enhanced by Tunisian aromatic plant extract without affecting cell growth and cell shape. This denotes that Tunisian aromatic plant can induce melanogenesis in B16 cells without causing transformation. In succeeding experiments, we found that Tunisian aromatic plant promoted melanogenesis without affecting tyrosinase protein expression. Moreover, we did not detect the phosphorylation of extracellular signal-regulated kinase 1 and 2 (ERK1/2), which are related to inhibition of melanogenesis.

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References

  1. Kim, Y.J., Uyama, H., 2005, Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. CMLS 62: 1707–1723.

    Article  CAS  PubMed  Google Scholar 

  2. Kim, D.S., Park, S.H., Kwon, S.B., Park, E.S., Huh, C.H., Youn, S.W., Park, K.C., 2005, Sphingosylphosphorylcholine-induced ERK activation inhibits melanin synthesis in human melanocytes. Pigment Cell Res. 19: 146–153.

    Article  Google Scholar 

  3. Lahlou, M., 2004, Methods to study the phytochemistry and bioactivity of essential oils. Phytother. Res. 18: 435–448.

    Article  CAS  PubMed  Google Scholar 

  4. Hosoi, J., Abe, E., Suda, T., Kuroki, T., 1985, Regulation of melanin synthesis of B16 mouse melanoma cells by 1 alpha, 25-dihydroxyvitamin D3 and retinoic acid. Cancer Res. 45: 1474–1478.

    CAS  PubMed  Google Scholar 

  5. Kim, D.S., Kim, S.Y., Park, S.H., Choi, Y.G., Kwon, S.B., Kim, M.K., Na, J.I., Youn, S.W., Park, K.C., 2005, Inhibitory effects of 4-n-Butylresorcinol on tyrosinase activity and melanin synthesis. Biol. Pharm. Bull. 28: 2216–2219.

    Article  CAS  PubMed  Google Scholar 

  6. Sugimoto, K., Nishimura, T., Nomura, K., Sugimoto, K., Kuriki, T., 2004, Inhibitory effects of α-Arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. Biol. Pharm. Bull. 27: 510–514.

    Article  CAS  PubMed  Google Scholar 

  7. Kawano, M., Imamura, T., Isoda, H., 2006, Methods for searching and evaluating effective hair growth regulation factors from Tunisian samples. J. Arid Land Studies 15: 443–446.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Alliance for Research on North Africa (ARENA), Graduate School Life and Environmental Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan

    Kyoko Matsuyama, Mitsuko Kawano & Hiroko Isoda

  2. Technopole de Borj-Cedria-Centre de Biotechnologie, 901, Hammam-Lif, 2050, Tunisia

    Mohamed Kchouk

  3. National Food Research Institute (NFRI), 2-1-12 Kannondai, Tsukuba Ibaraki, 305-8642, Japan

    Hiroshi Shinmoto

Authors
  1. Kyoko Matsuyama
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  2. Mitsuko Kawano
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  3. Mohamed Kchouk
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  4. Hiroshi Shinmoto
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  5. Hiroko Isoda
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Editor information

Editors and Affiliations

  1. Dept. Genetic Resources Technology, Kyushu University, Hakozaki 6-10-1, Fukuoka, 812-8581, Japan

    Sanetaka Shirahata

  2. Dept. Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, 606-8585, Japan

    Koji Ikura

  3. Graduate School of Biostudies, Kyoto University, Kyoto, 606-8502, Japan

    Masaya Nagao

  4. Dept. Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, 606-8585, Japan

    Akira Ichikawa

  5. Fac. Agriculture, Kyushu University, Hakozaki, Fukuoka, 812-8581, Japan

    Kiichiro Teruya

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© 2008 Springer Science+Business Media B.V.

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Matsuyama, K., Kawano, M., Kchouk, M., Shinmoto, H., Isoda, H. (2008). Effect of Tunisian Plant Extract on Melanogenesis. In: Shirahata, S., Ikura, K., Nagao, M., Ichikawa, A., Teruya, K. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 15. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9646-4_40

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