Fetal Diagnosis of Neural Tube Defect
Prenatal diagnosis or identification of NTD has been mentioned often above. Here I describe its beginnings. First, it must be understood that the main purpose of identifying NTD prenatally has been the pragmatic one of enabling selective abortion of affected fetuses (Nørgaard-Pedersen et al. 1985, Hendricks et al. 1988, Stoll et al. 1988, Alembik et al. 1997, Hume et al. 1996, Rankin et al. 2000, Ray et al. 2002, Cedergren and Selbing 2006). This brings us to consider the means of such identification and to the subject of prenatal diagnosis of NTD and its significance.
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