Searching for Effectors of Magnaporthe oryzae: A Multi-Faceted Genomics Approach
In 2005, a draft sequence of Magnaporthe oryzae isolate 70–15 genome was published (Dean et al. 2005). Complete rice genome sequence was also published in the same year (International Rice Genome Sequencing Project, 2005). As a result, study of the Magnaporthe-rice interaction has entered the “post-genomics” era. The challenge now is how to make use of this large amount of information to improve our understanding of this interaction. By employing genomics information, we are trying to identify and characterize Magnaporthe effectors directly involved in molecular interactions between the pathogen and the host. In this paper, we present a short review of phytopathogen effectors and Magnaporthe avirulence factors. We then briefly describe our current approach to identify new effectors from Magnaporthe.
KeywordsDNA polymorphisms Effector Signal peptide SuperSAGE
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