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Physiological Ecology of Environmental Saprophytic and Potentially Pathogenic Mycobacteria

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Physiological ecology refers to the study and identification of the physiological features of the environmental saprophytic and potentially pathogenic mycobacteria that are determinants of its regional and local distribution, its ecology. Although mycobacteria are slow growing relative to most other environmental micro-organisms, they persist in a number of habitats where suspended micro-organisms would be washed away. Furthermore, mycobacteria are found in habitats where there is reduced competition for nutrients and other micro-organisms, because of the physiochemical conditions and absence of readily degraded nutrients.

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References

  • Bardouniotis E, Ceri H, Olson ME (2003) Biofilm formation and biocide susceptibility testing of Mycobacterium fortuitum and Mycobacterium marinum. Curr. Microbiol. 46:28–32

    Article  PubMed  CAS  Google Scholar 

  • Bardouniotis E, Huddleston W, Ceri H, Olson ME (2001) Characterization of biofilm growth and biocide susceptibility testing of Mycobacterium phlei using the MBEC (TM) assay system. Fems Microbiol. Lett. 203:263–267

    PubMed  CAS  Google Scholar 

  • Bercovier H, Kafri O, Sela S (1986) Mycobacteria Possess A Surprisingly Small Number of Ribosomal-RNA Genes in Relation to the Size of Their Genome. Biochem. Biophys. Res. Commun. 136:1136–1141

    Article  PubMed  CAS  Google Scholar 

  • Bodmer T, Miltner E, Bermudez LE (2000) Mycobacterium avium resists exposure to the acidic conditions of the stomach. FEMS Microbiol. Lett. 182:45–49

    Article  PubMed  CAS  Google Scholar 

  • Boldrin B, Tiehm A, Fritzsche C (1993) Degradation of phenanthrene, fluorene, fluoranthene, and pyrene by a Mycobacterium sp. Appl. Environ. Microbiol. 59:1927–1930

    PubMed  CAS  Google Scholar 

  • Brennan PJ, Nikaido H (1995) The Envelope of Mycobacteria. Ann. Rev. Biochem.. 64:29–63

    Article  PubMed  CAS  Google Scholar 

  • Chapman JS, Bernard JS (1962) The tolerances of unclassified mycobacteria. I. Limits of pH tolerance. Am. Rev. Respir. Dis. 86:582–583

    CAS  Google Scholar 

  • Cirillo JD, Falkow S, Tompkins LS, Bermudez LE (1997) Interaction of Mycobacterium avium with environmental amoebae enhances virulence. Infect. Immun. 65:3759–3767

    PubMed  CAS  Google Scholar 

  • Davison MB, McCormack JG, Blacklock ZM, Dawson DJ, Tilse MH, Crimmins FB (1988) Bacteremia caused by Mycobacterium neoaurum. J. Clin. Microbiol. 26:762–764

    PubMed  CAS  Google Scholar 

  • De Groote MA, Pace NR, Fulton K, Falkinham JO, III (2006) Relationships between Mycobacterium isolates from patients with pulmonary mycobacterial infection and potting soils. Appl. Environ. Microbiol. 72:7602–7606

    Article  PubMed  Google Scholar 

  • Dick T, Lee BH, Murugasu-Oei B (1998) Oxygen depletion induced dormancy in Mycobacterium smegmatis. FEMS Microbiol. Lett. 163:159–164

    Article  PubMed  CAS  Google Scholar 

  • Donlan RM (2001) Biofilms and device-associated infections. Emerg. Infect. Dis. 7:277–281

    Article  PubMed  CAS  Google Scholar 

  • du Moulin GC, Stottmeier KD, Pelletier PA, Tsang AY, Hedley-Whyte J (1988) Concentration of Mycobacterium avium by hospital hot water systems. JAMA. 260:1599–1601

    Article  PubMed  Google Scholar 

  • Falkinham JO (2003) Factors influencing the chlorine susceptibility of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum. Appl. Environ. Microbiol. 69:5685–5689

    Article  PubMed  CAS  Google Scholar 

  • Falkinham JO, III (2007) Growth in catheter biofilms and antibiotic resistance of Mycobacterium avium. J. Med. Microbiol. 56:250–254

    Article  PubMed  Google Scholar 

  • Falkinham JO, III, Norton CD, LeChevallier MW (2001) Factors influencing numbers of Mycobacterium avium, Mycobacterium intracellulare, and other Mycobacteria in drinking water distribution systems. Appl. Environ. Microbiol. 67:1225–1231

    Article  PubMed  CAS  Google Scholar 

  • Flynn PM, Van HB, Gigliotti F (1988) Atypical mycobacterial infections of Hickman catheter exit sites. Pediatr. Infect. Dis. J. 7:510–513

    Article  PubMed  CAS  Google Scholar 

  • George KL, Falkinham JO, III (1986) Selective medium for the isolation and enumeration of Mycobacterium avium-intracellulare and M. scrofulaceum. Can. J. Microbiol. 32:10–14

    Article  PubMed  CAS  Google Scholar 

  • George SL, Schlesinger LS (1999) Mycobacterium neoaurum - An unusual cause of infection of vascular catheters: Case report and review. Clin. Infect. Dis. 28:682–683

    Article  PubMed  CAS  Google Scholar 

  • Hall-Stoodley L, Lappin-Scott H (1998) Biofilm formation by the rapidly growing mycobacterial species Mycobacterium fortuitum. FEMS Microbiol. Lett. 168:77–84

    Article  PubMed  CAS  Google Scholar 

  • Holland DJ, Chen SC, Chew WW, Gilbert GL (1994) Mycobacterium neoaurum infection of a Hickman catheter in an immunosuppressed patient. Clin. Infect. Dis. 18:1002–1003

    Article  PubMed  CAS  Google Scholar 

  • Iivanainen EK, Martikainen PJ, Raisanen ML, Katila ML (1997) Mycobacteria in boreal coniferous forest soils. Fems Microbiol. Ecol. 23:325–332

    Article  CAS  Google Scholar 

  • Kirschner RA, Parker BC, Falkinham JO, III (1992) Epidemiology of infection by nontuberculous mycobacteria. Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum in acid, brown-water swamps of the southeastern United States and their association with environmental variables. Am. Rev. Respir. Dis. 145:271–275

    Google Scholar 

  • Kirschner RA, Parker BC, Falkinham JO (1999) Humic and fulvic acids stimulate the growth of Mycobacterium avium. Fems Microbiol. Ecol. 30:327–332

    Article  PubMed  CAS  Google Scholar 

  • Kiska DL, Turenne CY, Dubansky AS, Domachowske JB (2004) First case report of catheter-related bacteremia due to “Mycobacterium lacticola”. J. Clin. Microbiol. 42: 2855–2857

    Article  PubMed  CAS  Google Scholar 

  • Maaloe O, Kjeldgaard N (1966) Control of macromolecular synthesis; a study of DNA, RNA, and protein synthesis in bacteria (Ed.: B. D. Davis). W.A. Benjamin, New York

    Google Scholar 

  • Nickel JC, Ruseska I, Wright JB, Costerton JW (1985) Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material. Antimicrob. Agents Chemother. 27:619–624

    PubMed  CAS  Google Scholar 

  • Nohynek LJ, Haggblom MM, Palleroni NJ, Kronqvist K, Nurmiaho Lassila EL, Salkinojasalonen M (1993) Characterization of A Mycobacterium-Fortuitum Strain Capable of Degrading Polychlorinated Phenolic-Compounds. Syst. Appl. Microbiol. 16:126–134

    Article  CAS  Google Scholar 

  • Ollar RA, Dale JW, Felder MS, Favate A (1990) The use of paraffin wax metabolism in the speciation of Mycobacterium avium-intracellulare. Tubercle. 71:23–28

    Article  PubMed  CAS  Google Scholar 

  • Parker BC, Ford MA, Gruft H, Falkinham JO, III (1983) Epidemiology of infection by nontuberculous mycobacteria. IV. Preferential aerosolization of Mycobacterium intracellulare from natural waters. Am. Rev. Respir. Dis. 128:652–656

    PubMed  CAS  Google Scholar 

  • Piddington DL, Kashkouli A, Buchmeier NA (2000) Growth of Mycobacterium tuberculosis in a defined medium is very restricted by acid pH and Mg(2+) levels. Infect. Immun. 68:4518–4522

    Article  PubMed  CAS  Google Scholar 

  • Portaels F, Pattyn SR (1982) Growth of mycobacteria in relation to the pH of the medium. Ann. Microbiol. (Paris). 133:213–221

    CAS  Google Scholar 

  • Poupin P, Truffaut N, Combourieu B, Besse P, Sancelme M, Veschambre H, Delort AM (1998) Degradation of morpholine by an environmental Mycobacterium strain involves a cytochrome P-450. Appl. Environ. Microbiol. 64: 159–165

    PubMed  CAS  Google Scholar 

  • Raad II, Vartivarian S, Khan A, Bodey GP (1991) Catheter-related infections caused by the Mycobacterium fortuitum complex: 15 cases and review. Rev. Infect. Dis. 13:1120–1125

    Article  PubMed  CAS  Google Scholar 

  • Rafii F, Selby AL, Newton RK, Cerniglia CE (1994) Reduction and mutagenic activation of nitroaromatic compounds by a Mycobacterium sp. Appl. Environ. Microbiol. 60:4263–4267

    PubMed  CAS  Google Scholar 

  • Schelonka RL, Ascher DP, McMahon DP, Drehner DM, Kuskie MR (1994) Catheter-related sepsis caused by Mycobacterium avium complex. Pediatr. Infect. Dis. J. 13:236–238

    Article  PubMed  CAS  Google Scholar 

  • Schulze-Robbecke R, Buchholtz K (1992) Heat susceptibility of aquatic mycobacteria. Appl. Environ. Microbiol. 58:1869–1873

    PubMed  CAS  Google Scholar 

  • Schulze-Robbecke R, Fischeder R (1989) Mycobacteria in biofilms. Zentralbl. Hyg. Umweltmed. 188:385–390

    PubMed  CAS  Google Scholar 

  • Schulze-Robbecke R, Janning B, Fischeder R (1992) Occurrence of mycobacteria in biofilm samples. Tuber. Lung Dis. 73:141–144

    Article  PubMed  CAS  Google Scholar 

  • Steed KA, Falkinham JO, III (2006) Effect of growth in biofilms on chlorine susceptibility of Mycobacterium avium and Mycobacterium intracellulare. Appl. Environ. Microbiol. 72:4007–4011

    Article  PubMed  CAS  Google Scholar 

  • Stormer RS, Falkinham JO, III (1989) Differences in antimicrobial susceptibility of pigmented and unpigmented colonial variants of Mycobacterium avium. J. Clin. Microbiol. 27:2459–2465

    PubMed  CAS  Google Scholar 

  • Thorel MF, Falkinham JO, Moreau RG (2004) Environmental mycobacteria from alpine and subalpine habitats. Fems Microbiol. Ecol. 49:343–347

    Article  PubMed  CAS  Google Scholar 

  • Torvinen E, Suomalainen S, Lehtola MJ, Miettinen IT, Zacheus O, Paulin L, Katila ML, Martikainen PJ (2004) Mycobacteria in water and loose deposits of drinking water distribution systems in Finland. Appl. Environ. Microbiol. 70:1973–1981

    Article  PubMed  CAS  Google Scholar 

  • Van Oss C, Gillman C, Neumann A (1975) Phagocytic Engulfment and Cell Adhesiveness. Marcel Dekker, Inc., New York.

    Google Scholar 

  • Wayne LG, Hayes LG (1996) An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect. Immun. 64:2062–2069

    PubMed  CAS  Google Scholar 

  • Wendt SL, George KL, Parker BC, Gruft H, Falkinham JO, III (1980) Epidemiology of infection by nontuberculous Mycobacteria. III. Isolation of potentially pathogenic mycobacteria from aerosols. Am. Rev. Respir. Dis. 122:259–263

    PubMed  CAS  Google Scholar 

  • Woo PC, Tsoi HW, Leung KW, Lum PN, Leung AS, Ma CH, Kam KM, Yuen KY (2000) Identification of Mycobacterium neoaurum isolated from a neutropenic patient with catheter-related bacteremia by 16S rRNA sequencing. J. Clin. Microbiol. 38:3515–3517

    PubMed  CAS  Google Scholar 

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Correspondence to J.O. Falkinham III .

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Falkinham, J. (2009). Physiological Ecology of Environmental Saprophytic and Potentially Pathogenic Mycobacteria. In: The Ecology of Mycobacteria: Impact on Animal's and Human's Health. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9413-2_4

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