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Mitochondria and Immunosenescence

  • Pazit Beckerman
  • Arie Ben Yehuda

The immune system undergoes age-associated changes, that affect its response to infections and cancer, and contributes to the organism’s aging and its associated pathologies. An eminent hypothesis to explain the aging process, most supported by experimental data, is the mitochondrial free radical theory. Evidence is accumulating, linking mitochondrial oxidative damage and apoptosis to immunosenescence.

Keywords

Mitochondrial Membrane Potential Mitochondrial Permeability Transition Mitochondrial Permeability Transition Pore Replicative Senescence Increase Reactive Oxygen Species Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Pazit Beckerman
    • 1
  • Arie Ben Yehuda
    • 1
  1. 1.The Department of MedicineUniversity Hospital KeremKerem

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