The immune system undergoes age-associated changes, that affect its response to infections and cancer, and contributes to the organism’s aging and its associated pathologies. An eminent hypothesis to explain the aging process, most supported by experimental data, is the mitochondrial free radical theory. Evidence is accumulating, linking mitochondrial oxidative damage and apoptosis to immunosenescence.
KeywordsOsteoporosis Glutathione Adenosine Oligomerization Glucocorticoid
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