Advertisement

New Method for Ultrasound Contrast Imaging Using Frequency-Modulated Transmission

  • H. Ohuchi
  • N. Kamiyama
  • T. Kawagishi
  • T. Imamura
  • T. Asanuma
  • H. Ishikura
  • S. Beppu
Conference paper
Part of the Acoustical Imaging book series (ACIM, volume 29)

Abstract

In diagnostic ultrasound imaging, microbubble-based contrast agents are currently used to enhance blood flow signals. The microbubbles in the blood vessels have various diameters and various resonant frequencies. Therefore, only some bubbles will be stimulated by a transmission pulse with a single frequency component. In this report, we propose a multiple-pulse transmission method with different frequencies to stimulate more microbubbles. We have confirmed both an increase in bubble echoes and the suppression of tissue echoes with this method. In phantom experiments, wideband bubble echoes were obtained using the proposed method, and the bubble-tissue ratio was improved by 8.3 dB as compared with the conventional second-harmonic method. In animal experiments, the tissue echoes were adequately suppressed as compared with conventional second-harmonic images.

Key words

Ultrasound contrast agent Microbubble Nonlinear Frequency modulation 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    P.N. Burns et al., “Pulse inversion imaging of liver blood flow: Improved method for characterizing focal masses with microbubble contrast”. Invest. Radiology, 35, 58–71 (2000).CrossRefGoogle Scholar
  2. 2.
    K. Morgan, J. Allen, et al., “Experimental and theoretical evaluation of microbubble behavior: Effect of transmitted phase and bubble size”, IEEE Trans. on UFFC, 47(6), 1494–1509 (2000).Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • H. Ohuchi
    • 1
    • 2
  • N. Kamiyama
    • 1
    • 2
  • T. Kawagishi
    • 1
    • 2
  • T. Imamura
    • 1
    • 2
  • T. Asanuma
    • 1
    • 2
  • H. Ishikura
    • 1
    • 2
  • S. Beppu
    • 1
    • 2
  1. 1.Toshiba Medical Systems Corp.OtawaraJapan
  2. 2.School of Allied Health Sciences, Faculty of MedicineOsaka UniversityJapan

Personalised recommendations