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Mechanical Properties of Brain Tissue: Characterisation and Constitutive Modelling

  • Chapter
Mechanosensitivity of the Nervous System

Part of the book series: Mechanosensitivity in Cells and Tissues ((MECT,volume 2))

Abstract

The head is often considered as the most critical region of the human body for life-threatening injuries sustained in accidents. In order to develop effective protective measures, a better understanding of the process of injury development in the brain is required. Finite Element (FE) models are being developed, in order to predict the mechanical response of the contents of the head during impact. To obtain accurate predictions of the mechanical response of the brain, an accurate description of the mechanical behaviour of brain tissue is required. However, up to now no universally accepted data set for the constitutive response of brain tissue exists. The large variation in material properties reported may be caused by differences in testing methods and protocols used. An overview of studies on the mechanical properties of brain tissue is presented, focusing on testing methods. Furthermore, the large strain mechanical response of brain tissue as well as modelling approaches for this behaviour are discussed.

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Authors and Affiliations

  1. Materials Technology Institute, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands

    J.A.W. van Dommelen

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  1. J.A.W. van Dommelen
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  2. M. Hrapko
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  3. G.W.M. Peters
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Editors and Affiliations

  1. Dept. Fundamental & Applied Physiology, Russian State Medical University, Ostrovitjanova Str. 1, Moscow, Russia 117997

    Andre Kamkim  & Irina Kiseleva  & 

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van Dommelen, J., Hrapko, M., Peters, G. (2009). Mechanical Properties of Brain Tissue: Characterisation and Constitutive Modelling. In: Kamkim, A., Kiseleva, I. (eds) Mechanosensitivity of the Nervous System. Mechanosensitivity in Cells and Tissues, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8716-5_12

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