Introduction to Clinical Research and Study Designs
This chapter addresses some of the central concepts related to clinical research and what is meant by the strength of scientific evidence. We also begin to discuss the different clinical research designs along with their respective strengths and weaknesses.
KeywordsNull Hypothesis Randomized Clinical Trial Statistical Hypothesis Research Hypothesis Passive Smoke
Unable to display preview. Download preview PDF.
- 1.Parker_Palmer. http://en.wikipedia.org/wiki/Parker_Palmer
- 2.Vickers AJ. Michael Jordan won’t accept the null hypothesis: notes on interpreting high P values. Medscape. 2006; 7(1).Google Scholar
- 3.The Null Logic of Hypothesis Testing. http://www.shsu.edu/∼icc_cmf/cj_787/research6.doc
- 4.Blackstone. Cited in The Null Logic of Hypothesis Testing. 2 Bl. Com. C. 27, margin page 358, ad finem. Available at: http://www.shsu.edu/∼icc_cmf/cj_787/research6.doc
- 6.Cited in Sartwell P and Nathanson N. Epidemiologic Reviews. 1993.Google Scholar
- 9.von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med. Oct 16, 2007; 147(8):573–577.Google Scholar