Gene function in glial-neuronal interactions

Abstract

Neurons and glial cells constitute the major components of the nervous system. Although they display distinct roles, their continuous interactions are the gage for appropriate development and function of such a complex tissue. For this reason, the more we will understand the molecular and cellular bases of neuron-glia interactions, the more we will be able to unravel the complex processes underlying the differentiation, the function and the survival of these two cell types.

Keywords

Migration Tyrosine Retina Germinal Expense 

Abbreviations

AM

Anterior margin

bHLH

Basic helix-loop-helix

BMPs

Bone morphogenetic proteins

CNS

Central nervous system

cpn

Contralateral axon

DER

Drosophila EGF receptor

DRG

Dorsal root ganglion

EGF

Early growth factor

EGFR

Early growth factor receptor

GBS

Glide-binding site

GFAP

Glial fibrillary acidic protein

GFP

Green fluorescent protein

Glide\Gcm

Glia cell deficient\ Glia cell missing

GPI

Glycosylphosphatidylinositol

ipn

Ipsilateral axon

LG

Longitudinal glia

MAG

Myelin associated glycoprotein

MAPK

MAP kinase

MF

Morphogenetic furrow

MG

Midline glia

Notch 1 IC

Notch 1 intracellular domain

NRG-1

Neuregulin-1

OLs

Oligodendrocytes

Omgp

Oligodendrocyte myelin glycoprotein

OLPs

Oligodendrocyte precursors

p75NTR

p75 neurotrophin receptor

pMN

domain Motor neuron progenitor domain

PNS

Peripheral nervous system

R

Photoreceptor

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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  1. 1.Institut de Génétique et Biologie Moléculaire et CellulaireIGBMC/CNRS/ULP/INSERMIllkirch, c.u. de StrasbourgFrance

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