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Tumors of Serous Cavities

Mesotheliomata may be pleural, peritoneal, or pericardial. Malignant pleural mesothelioma is an aggressive neoplasm of the serosal lining of the pleural cavity, which arises from undifferentiated mesothelial cells representing the adult remnants of the surface celomic mesoderm. Mesothelial cells may give rise to both the lining epithelial cells (which express Keratin) and the paucicellular submesothelial layer. The etiology of mesothelioma is primarily associated with environmental factors, particularly exposure to asbestos and smoking. The latency period can be 10–20 years.

Subtypes of mesothelioma are:
  • Epithelioid (the most common)

  • Sarcomatous (a much more aggressive form)

  • Biphasic or mixed (a combination of both of the other cell types)

Keywords

Mesothelial Cell Malignant Pleural Mesothelioma Synovial Sarcoma Malignant Mesothelioma Serous Cavity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer 2007

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