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Using Yeast Tools to Dissect the Action of Anticancer Drugs: Mechanisms of Enzyme Inhibition and Cell Killing by Agents Targeting DNA Topoisomerases

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Keywords

  • Repair Pathway
  • Replication Fork
  • Covalent Complex
  • Mutation Confer Drug Resistance
  • Top1 Poison

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  • DOI: 10.1007/978-1-4020-5963-6_16
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Rogojina, A.T., Li, Z., Nitiss, K.C., Nitiss, J.L. (2007). Using Yeast Tools to Dissect the Action of Anticancer Drugs: Mechanisms of Enzyme Inhibition and Cell Killing by Agents Targeting DNA Topoisomerases. In: Nitiss, J.L., Heitman, J. (eds) Yeast as a Tool in Cancer Research. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5963-6_16

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