Surgical management of patients with metastatic breast cancer

  • Adam I. Riker
  • SuHu Liu
  • Mona Hagmaier
  • Matthew J. D. D'lessio
  • Charles E. Cox
Part of the Cancer Metastasis – Biology and Treatment book series (CMBT, volume 11)


Metastatic breast cancer can be a difficult problem to manage surgically as the sole mode of treatment. In certain cases, surgical management is the initial treatment of choice, such as sentinel lymph node mapping and nodal dissections for locoregional control. Other situations, such as metastatic breast cancer to solid organs, such as the brain, liver, and lung, are dictated by individual patient characteristics and the overall clinical situation. Clearly, surgery has become a part of the broader management schema in treating patients with metastatic breast cancer, with developing technologies, such as stereotactic radiosurgery, greatly enhancing our ability to treat such patients. Surgery is a single, but important, tool that should be combined with other modes of therapy, such as hormonal therapy and radiation therapy, to optimize treatment strategies and patient outcomes. There remains a fair amount of controversy as to the clinical significance of micrometastatic disease within the lymph nodes and bone marrow, a relevant topic that is actively being examined by clinicians and researchers from around the world. Regardless, the role of surgery for patients with metastatic breast cancer has become a central part of the multidisciplinary care of such patients, with this review providing an overview of the various aspects of surgical management of metastatic disease.


metastastic breast cancer micrometastatic sentinel lymph node surgical management locoregional recurrence bone metastasis lung metastasis liver metastasis 


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Copyright information

© Springer 2007

Authors and Affiliations

  • Adam I. Riker
    • 1
  • SuHu Liu
    • 2
  • Mona Hagmaier
    • 3
  • Matthew J. D. D'lessio
    • 4
  • Charles E. Cox
    • 5
  1. 1.Mitchell Cancer InstituteUniversity of South AlabamaUSA
  2. 2.University of South Alabama-Mitchell Cancer InstituteUSA
  3. 3.University of South Alabama-Mitchell Cancer InstituteUSA
  4. 4.University of South Alabama-Mitchell Cancer InstituteUSA
  5. 5.Moffitt Cancer CenterUniversity of South FloridaTampaUSA

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