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Brilliant Light in Life and Material Sciences pp 267–272Cite as

SYNCHROTRON FT-IR SPECTROSCOPY OF HUMAN BONES. THE EFFECT OF AGING

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Part of the book series: NATO Security through Science Series ((NASTB))

Abstract

The Synchrotron micro-FT-IR spectroscopy was used to investigate the structural changes of human bones, which are produced upon irradiation. It was observed that after irradiation with a dose of 40 Gy up to 119 Gy the band at 1660 cm-1, which corresponds to the absorption of the Amide I group (-NH-CO-) and indicates that the collagen exists in α-helix, shows considerable changes upon irradiation resulting that the collagen looses its structure from α-helix to random coil. Considerable changes were also observed in the region of the spectra between 900 cm-1 and 1200 cm-1 where the phosphate groups (v3PO4 3-) of hydroxyapatite absorb. These bands change in intensity and shape. These findings show that the irradiation of human bones leads to damage of the main components of bone tissues.

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REFERENCES

  1. M. Petra, J. Anastassopoulou, T. Theologis, T. Theophanides, Synchrotron micro-FT-IR spectroscopic evaluation of normal paediatric human bone, J. Mol. Str., 733 (2005) 101–110, and references therein.

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  3. T. Theophanides, “Interaction of Metal Ions with Nucleic Acids”, in Infrared and Raman Spectroscopy Applied to Biological Molecules, (ed. T. Theophanides), D. Reidel Publishing Co, Dodrecht, Holland, p. 185 (1979).

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Author information

Authors and Affiliations

  1. Chemical Engineering Department, Radiation Chemistry and Biospectroscopy, National Technical University of Athens, Athens, Greece

    P. Kolovou & J. Anastassopoulou

Authors
  1. P. Kolovou
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  2. J. Anastassopoulou
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Editor information

Editors and Affiliations

  1. Center for the Advancement of Natural Discoveries Using Light Emission, Yerevan, Armenia

    Vasili Tsakanov

  2. Advanced Physics Department and SSRL/SLAC, Stanford University, Stanford, CA, U.S.A.

    Helmut Wiedemann

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© 2007 Springer

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Kolovou, P., Anastassopoulou, J. (2007). SYNCHROTRON FT-IR SPECTROSCOPY OF HUMAN BONES. THE EFFECT OF AGING. In: Tsakanov, V., Wiedemann, H. (eds) Brilliant Light in Life and Material Sciences. NATO Security through Science Series. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5724-3_24

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