Screening Strategies for Iron Chelators in Serum Free Media

  • Joanne Keenan
  • Dermot Pearson
  • Martin Clynes
Conference paper


A variety of iron chelators, including recombinant human transferrin, were evaluated as replacements to holo human transferrin on a number of industrially relevant cell lines (MDCK, BHK-21 and Vero). The results showed that short term screening over one passage is not necessarily adequate to select a suitable transferrin replacement.


MDCK Cell Iron Chelator Screening Assay Ferrous Sulphate Human Transferrin 
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Copyright information

© Springer 2007

Authors and Affiliations

  • Joanne Keenan
    • 1
  • Dermot Pearson
    • 2
  • Martin Clynes
    • 1
  1. 1.National Institute for Cellular BiotechnologyDublin City UniversityIreland
  2. 2.Delta BiotechnologyLtdNottinghamUK

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