Evaluation of a Scalable Disposable Bioreactor System for Manufacturing of Mammalian Cell Based Biopharmaceuticals

  • Silke Langhammer
  • Marco Riedel
  • Hikmat Bushnaq-Josting
  • René Brecht
  • Ralf Pörtner
  • Uwe Marx
Conference paper

Abstract

The use of disposable equipment in biopharmaceutical up- and downstream processes has increased in the last few years. This results in higher process flexibility and safety at reduced CIP and SIP efforts. The lack of robust scaleable disposable bioreactors initiated our own engagement in this area.

Keywords

Permeability Toxicity Filtration Steam 

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Copyright information

© Springer 2007

Authors and Affiliations

  • Silke Langhammer
    • 1
  • Marco Riedel
    • 1
  • Hikmat Bushnaq-Josting
    • 1
  • René Brecht
    • 1
  • Ralf Pörtner
    • 2
  • Uwe Marx
    • 1
  1. 1.ProBioGen AGBerlinGermany
  2. 2.Hamburg University of TechnologyHamburgGermany

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