Abstract
Using Computational Fluid Dynamics, a method for the design of animal cell culture reactors is proposed. This approach is based on the concept of Fluid Stress Distribution and on the calculation of animal cell paths.
Keywords
- Computational Fluid Dynamics
- Particle Image Velocimetry
- Animal Cell Culture
- Hydrodynamic Stress
- Roller Bottle
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References
Haut, B., Ben Amor, H., Coulon, A., Jacquet, A., Halloin, V. 2003. Hydrodynamics and mass transfer in a Couette-Taylor bioreactor for the culture of animal cells, Chem. Eng. Sci. 58 777–784.
Morsi, S.A. and Alexander, A.J. 1972, An investigation of particle trajectories in two-phase flow systems, J. Fluid Mech. 55 193–208.
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© 2007 Springer
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Olmos, E., Fischbach, N., Marc, A. (2007). Computational Fluid Dynamics Applied to Laboratory Scale Cell Culture Reactors for the Prediction of Hydrodynamic Stress. In: Smith, R. (eds) Cell Technology for Cell Products., vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5476-1_103
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DOI: https://doi.org/10.1007/978-1-4020-5476-1_103
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5475-4
Online ISBN: 978-1-4020-5476-1
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