The Covalently Linked Sacculus: the Nona-Muropeptide Model

  • Arthur L. Koch


A bacterial cell wears a stress-bearing suit of armor: the sacculus or exoskeleton. In E. coli it is composed of hundreds of thousands of disaccharide penta-muropeptides polymerized together. There are even more in the Grampositive B. subtilis. Of course, the penta-muropeptide units are held together by strong covalent bonds, as shown in Figure 6.1, and these individual units are bound together with additional covalent bonds to make the sacculus strong.


Hydroxyl Saccharide Amide Acetyl Penta 


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Copyright information

© Springer 2007

Authors and Affiliations

  • Arthur L. Koch
    • 1
  1. 1.Indiana UniversityBloomingtonUSA

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