Abstract
In this chapter we introduce the concept of bioartificial neuronal networks, that is networks of biological neurons cultured in-vitro and coupled to Micro Transducer Arrays (MTAs). In-vitro cultured neurons extracted from rats or mice embryos form a bi-dimensional physical model of the brain and, in spite of their simplified level of organization, are an useful framework to study information processing in the nervous system. One of the peculiar aspects is the possibility to chronically (i.e., for several days or weeks) stimulate at and record from multiple sites at the same time, thus establishing a bi-directional interface between a neuronal (i.e. biological) system and an artificial device. This experimental framework can be utilized as a new paradigm for studying novel and advanced neuro-electronic interface.
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Martinoia, S., Chiappalone, M., Vato, A. (2004). Bioartificial Neuronal Networks: Coupling Networks of Biological Neurons to Microtransducer Arrays. In: Valle, M. (eds) Smart Adaptive Systems on Silicon. Springer, Boston, MA. https://doi.org/10.1007/978-1-4020-2782-6_17
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DOI: https://doi.org/10.1007/978-1-4020-2782-6_17
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