Cytokinin Biosynthesis and Metabolism

  • Hitoshi Sakakibara


Since the discovery of cytokinins in the 1950s, it has been clearly established that they play an important role in various processes in the growth and development of plants, including the promotion of cell division, the counteraction of senescence, the regulation of apical dominance and the transmission of nutritional signals. Kinetin (Fig. 1a) was the first substance to be identified as a cytokinin, and although it was isolated from autoclaved herring sperm DNA (34) it is not naturally produced and has not been found in living plants. The naturally occurring cytokinin trans-zeatin (tZ, Fig. 1b) was first isolated from immature maize endosperm in the early 1960s (26). In the following 40 years, several cytokinin species have been identified from various plant species (35, 43). These studies demonstrated that natural plant cytokinins are adenines which have substituted at the N6 terminal either an isoprene-derived side chain (isoprenoid cytokinins), or an aromatic derivative side chain (aromatic cytokinins).


Purine Nucleoside Phosphorylase Cytokinin Oxidase Cytokinin Biosynthesis Adenine Phosphoribosyltransferase Cytokinin Metabolism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  1. 1.Plant Science CenterTsurumiJapan

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