Abstract
The effective combination of biological and physical methods in analytical device could provide the basis for direct detection of wide range of analytes with great sensitivity and specificity. The main aim of this study is to briefly present the current state in construction of biosensors based on conducting polymers. Current state of research on π-π conjugated polymer polypyrrole based biosensors is presented. The biological recognition parts of reviewed biosensors were based on polypyrrole doped or covalently modified by enzymes and other proteins. Future perspectives of polypyrrole application in hybrid biosensors based on dual (optical and electrochemical) detection system are discussed. Investigations of polypyrrole show that florescence of this conjugated polymer is undetectable. It can be successfully exploited as the immobilization matrix in fluorescence based biosensors, however.
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Ramanaviciene, A., Ramanavicius, A. (2004). Towards the Hybrid Biosensors Based on Biocompatible Conducting Polymers. In: Shur, M.S., Žukauskas, A. (eds) UV Solid-State Light Emitters and Detectors. NATO Science Series, vol 144. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-2103-9_25
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DOI: https://doi.org/10.1007/978-1-4020-2103-9_25
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