• Margaret L. Vickery
  • Brian Vickery


Polyketides form a large class of compounds found extensively in fungi and also, to a lesser extent, in higher plants. The majority are aromatic derivatives, but alicyclic compounds also occur. Although also biosynthesised by the acetate-malonate pathway, true polyketides are distinguished from fatty acids and their derivatives by their mode of biogenesis. This involves a hypothetical chain of alternating keto and methylene groups (Figure 4.1), whereas fatty acid precursors contain only methylene groups, the malonyl keto group being reduced after each condensation (Chapter 3).


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© Margaret L. Vickery and Brian Vickery 1981

Authors and Affiliations

  • Margaret L. Vickery
  • Brian Vickery

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