Viruses are the simplest entities able to reproduce and the fact that they are able to maintain and replicate, thus conserving their genetic continuity, is the only link they have with organisms known to be ‘alive’. Because they require a living cell in which to replicate their reproductive cycle is unique amongst living organisms.
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12.4 References and Further Reading
- Bauer, D. J. (1972). Thiosemicarbazones. In Chemotherapy of Viral Diseases, Vol. 1 (D. J. Bauer, ed.). Pergamon Press, OxfordGoogle Scholar
- Galbraith, A. W. (1976). An appraisal of amantadine in A2 influenza. In Symmetrel in Virology (C. A. S. Wink, ed.). Geigy PharmaceuticalGoogle Scholar
- Galbraith, A. W., Schild, G. C., Potter, C. W. and Watson, G. I. (1973). The therapeutic effect of amantadine in influenza occurring during the winter of 1971–2 assessed by double-blind study. J. R. Coll. gen. Practit., 23, 34–37Google Scholar
- Hermans, I. E. (1977). Antiviral agents. Mayo Clin. Proc., 52, 683–6Google Scholar
- Joklik, W. K. (1968). Studies on the mode of action of two antiviral agents: isatin-β-thiosemicarbazone and interferon. In Medical and Applied Virology (M. Sanders, and E. H. Lennette, eds). Green, St Louis, pp. 299–326Google Scholar
- Katz, E. Margolith, E. Felix, H. and Winer, B. (1978). Synthesis of vaccinia viral RNA and proteins in the presence of isatin-β-thiosemicarbazone. Curr. Chemother., 1, 330–2Google Scholar
- Kaufman, H. E. and Abel, R. (1974). Abstract No. 40, 14th Interscience Conference on Antimicrobial Agents and ChemotherapyGoogle Scholar
- Metz, D. H. Interferon and interferon inducers. Adv. Drug Res., 10, 101–56Google Scholar
- Oxford, J. S. and Williams, J. D. (1975). Chemotherapy and control of influenza. J. antimicrob. Chemother., 1, Suppl.Google Scholar
- Stellwagen, R. H. and Tomkins, G. M. (1971). Differential effect of 5-bromodeoxyuridine on concentrations of specific enzymes in hepatoma cells in culture (tyrosine aminotransferase/alanine aminotransferase/dehydrogenases/acid phosphatase/inhibition of synthesis). Proc. natn. Acad. Sci. U.S.A., 68, 1147–50CrossRefGoogle Scholar
- Streeter, D. G., Witkowski, J. T., Khare, G. P., Sidwell, R. W., Bauer, R. J., Robins, R. K. and Simon, L. N. (1976). Mechanisms of action of 1-β-D-ribofuranosyl-1, 2,4-triazole-3-carboxamide (virazole), a new broad-spectrum antiviral agent. Proc. natn. Acad. Sci. U.S.A., 70, 1174–8CrossRefGoogle Scholar
- Tyrrell, D. A. J. (1976). Interferon and its Clinical Potential. Heinemann Medical, LondonGoogle Scholar
- World Health Organisation (Editorial). (1972). Influenza prophylaxis with amantadine. WHO Bull. 8, 84–7Google Scholar