Antifungal Agents

  • David Edwards
Chapter

Abstract

In marked contrast to antibactieral chemotherapy there are very few agents available for the treatment of fungal infection. The reasons for this are mainly because the majority of fungal infections are not life-threatening to man, are far less common than bacterial infections, and, because they are eukaryotic pathogens, it is difficult to develop drugs which are specific for fungi without being concomitantly toxic to man. Because of these reasons the impetus for the development of new antifungal drugs is far less than that for antibacterials. However, the situation may change since fungal infection is increasing. This is due not only the increased use of broad-spectrum antibacterial antibiotics which enable fungi to infect secondarily, but also the use of corticosteroids and immunosuppressive drugs which produce the same effect.

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11.8 References and Further Reading

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© David Edwards 1980

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