Skip to main content
  • 487 Accesses

Abstract

Gases and volatile substances are encountered in pharmacy mainly as anaesthetic gases, volatile drugs and aerosol propellants. This chapter deals briefly with the properties of gases and vapours, including the variation of the vapour pressure above a solution with the composition of the solution and the temperature. The factors governing the solubility of gases in liquids are reviewed and related to the solubility of anaesthetic gases in the complex solvent systems of blood and tissues.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. K. D. Ertel, R. A. Heasley, C. Koegel, A. Chakrabarti and J. T. Carstensen. J. Pharm. Sci. 79, 552 (1990)

    Article  CAS  PubMed  Google Scholar 

  2. J. Liu, M. J. Laster, S. Taheri, E. I. Eger, B.S. Chortkoffand M. J. Halsey. Anesth. Analg. 19, 1049 (1994)

    Google Scholar 

  3. D. D. Koblin, B. S. Chortkoff, M. J. Laster, E. I. Eiger, M. J. Halsey and P. Ionescu. Anesth. Analg. 19, 1043 (1994)

    Google Scholar 

  4. E. I. Eger. Anaesthetic Uptake and Action, Williams and Wilkins, Baltimore, 1974, Chapter 9

    Google Scholar 

  5. L. J. Laasberg and J. Redley-Whyte. Anesthesiology 32, 351 (1970)

    Article  CAS  PubMed  Google Scholar 

  6. P. D. Wagner, P. F. Naumann and R. B. Laravuso. J. Appl. Physiol. 36, 600 (1974)

    CAS  PubMed  Google Scholar 

  7. R. A. Saraiva, B. A. Willis, A. Steward, J. N. Lunn and W. W. Mapleson. Br. J. Anaesth. 49, 115 (1977)

    Article  CAS  PubMed  Google Scholar 

  8. B. M. Q. Weaver and A. I. Webb. Br. J. Anaesth. 53, 487 (1981)

    Article  CAS  PubMed  Google Scholar 

  9. H. J. Lowe and K. Hagler. In Gas Chromatography in Biology and Medicine (R. Porter, ed.), Churchill, London, 1969, pp. 86–112

    Google Scholar 

  10. K. Kitani and K. Winkler. Scand. J. Clin. Lab. Invest. 29, 173 (1972)

    Article  CAS  PubMed  Google Scholar 

  11. G. A. Gregory and E. I. Eger. Fedn. Proc. 27, 705 (1968)

    Google Scholar 

  12. B. P. Schoenborn. Nature 214, 1120 (1967)

    Article  CAS  PubMed  Google Scholar 

  13. C. M. Coburn and E. I. Eger. Anesth. Analg. 65, 960 (1986)

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Copyright information

© 1998 A. T. Florence and D. Attwood

About this chapter

Cite this chapter

Florence, A.T., Attwood, D. (1998). Gases and Volatile Agents. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-14416-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-349-14416-7_3

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-0-333-69081-9

  • Online ISBN: 978-1-349-14416-7

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics