Pulmonary surfactant-associated proteins: their role in surface tension reduction

  • Fred Possmayer
  • Amanda Cockshutt
  • Shou-Hwa Yu


It is generally, albeit not universally [1,2], accepted that pulmonary surfactant stabilizes the lung by lowering the surface tension at the air-water interface of the alveoli. The requirement for pulmonary surfactant is particularly critical at birth when the newborn infant must clear its lungs of fetal pulmonary fluid and establish regular air breathing. Indeed, as outlined in detail in other chapters of this book, treatment of prematurely delivered infants with extracts of bovine or porcine surfactant leads to a significant reduction in the incidence and in the intensity of the respiratory distress syndrome of the neonate [3–5].


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Copyright information

© Macmillan Publishers Limited 1991

Authors and Affiliations

  • Fred Possmayer
  • Amanda Cockshutt
  • Shou-Hwa Yu

There are no affiliations available

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