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Analysis of the Assembly of the HIV Core by Electron Microscope Tomography

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Retroviral Proteases

Abstract

Both the proteolytic processing of the p55 gag precursor protein of HIV, myristilation of the p17 (MA) protein, and their morphological rearrangement are necessary to generate structurally mature virus particles (Dahlberg, 1988; Haseltine, 1989). This sequence of events would parallell the observations with e.g. Friend murine oncoviruses, also indicating that a late stage of virus maturation would be accompanied by the production of infectious virus (Katoh et al., 1985).

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© 1990 Macmillan Publishers Limited

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Höglund, S. et al. (1990). Analysis of the Assembly of the HIV Core by Electron Microscope Tomography. In: Pearl, L.H. (eds) Retroviral Proteases. Palgrave, London. https://doi.org/10.1007/978-1-349-11907-3_16

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  • DOI: https://doi.org/10.1007/978-1-349-11907-3_16

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-0-333-53612-4

  • Online ISBN: 978-1-349-11907-3

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