The Human Chromosome Map

  • T. Andrews


In order to map the human genome, the gene, as indicated by expressed gene products, abnormal phenotypes, or markers representing it, must first be assigned to a particular chromosome (from Greek, khroma, colour, and soma, body). For some genes, analysis of pedigree data alone may confirm their localisation. The first gene assignment, in 1911, came with the demonstration that red-green colour blindness followed an X-linked pattern of inheritance, and the gene was therefore located on the X chromosome. This human gene assignment was made at a time when there was no physical evidence for the chromosomal sex-determining mechanism in man and long before the chromosome number had been determined


Human Chromosome Angelman Syndrome Specific Chromosome Region Structural Chromosome Abnormality Chromosome Banding Technique 
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© The Galton Institute 1991

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  • T. Andrews

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