Multivariate Support for Three Distinct Approaches to the Assessment of Respiratory Sensation in Patients with Obstructive Lung Disease

  • Andrew Harver
  • Donald A. Mahler
  • J. Andrew Daubenspeck
  • Joan F. McGovern
Part of the Wenner-Gren Center International Symposium Series book series (WGS)


Dyspnea is a common complaint of patients with obstructive airway disease (OAD). It is the major reason that both occupational and recreational activities are limited in such patients. Accordingly, issues surrounding measurement of shortness of breath in patients with obstructive lung disease have received increasing attention (e.g., Altose, 1985; Killian, 1985). Reliable assessment of symptoms is important for many reasons including the evaluation of symptom severity, the management of breathlessness, and the elucidation of physiologic mechanisms subserving respiratory sensation.


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  1. Altose, M.D. (1985). Assessment and Management of Breathlessness. Chest, 88(Suppl.), 77–83.CrossRefGoogle Scholar
  2. Black, L.F., and Hyatt, R.E. (1969). Maximal Respiratory Pressures: Normal Values and Relationship to Age and Sex. Am. Rev. Respir. Dis., 99, 696–702.Google Scholar
  3. Borg, G.A.V. (1982). Psychophysical Bases of Perceived Exertion. Med. Sci. Sports Exer., 14, 377–381.Google Scholar
  4. Crapo, R.O., and Morris, A.H. (1981). Standardized Single Breath Normal Values for Carbon Monoxide Diffusing Capacity. Am. Rev. Respir. Dis., 123, 185–189.Google Scholar
  5. Dosman, J., Bode, F., Urbanetti, J., Martin, R., and Macklem, P.T. (1975). The Use of Helium-Oxygen Mixture During Maximum Expiratory Flow to Demonstrate Obstruction in Small Airways in Smokers. J. Clin. Invest., 55, 1090–1099.CrossRefGoogle Scholar
  6. Killian, K.J. (1985). The Objective Measurement of Breathlessness. Chest, 88(Suppl.), 84–90.CrossRefGoogle Scholar
  7. Killian, K.J., and Jones, N.L. (1984). The Use of Exercise Testing and Other Methods in the Investigation of Dyspnea. Clin. Chest Med., 5, 99–108.Google Scholar
  8. Lawrason, J.D., Harver, A., and Mahler, D.A. (1987). Comparison of Psychophysical, Clinical, and Exercise Methods for Quantifying Breathlessness in Obstructive Airway Disease. Am. Rev. Respir. Dis., 135, A192 (Abstract).Google Scholar
  9. Lindeman, R.H., Merenda, P.F., and Gold, R.Z. (1980). Introduction to bivariate and multivariate analysis. Scott and Foresman, Glenview, IL.Google Scholar
  10. Mahler, D.A., and Harver, A. (1987). Minimizing the Effects of Dyspnea in COPD Patients. J. Respir. Dis., 8, 23–34.Google Scholar
  11. Mahler, D.A., Rosiello, R.A., Harver, A., Lentine, T., McGovern, J.F., and Daubenspeck, J.A. (1987). Comparison of Clinical Dyspnea Ratings and Psychophysical Measurements of Respiratory Sensation in Obstructive Airway Disease. Am. Rev. Resp, Dis., 135, 1229–1233.CrossRefGoogle Scholar
  12. Mahler, D.A., Weinberg, D.H., Wells, C.K., and Feinstein, A.R. (1984). The Measurement of Dyspnea: Contents, Interobserver Agreement, and Physiologic Correlates of Two New Clinical Indices. Chest, 85, 751–758.CrossRefGoogle Scholar
  13. Morris, J.F., Koski, A., and Johnson, L.C. (1971). Spirometric Methods for Healthy Nonsmoking Adults. Am. Rev. Respir. Dis., 103, 57–67.Google Scholar
  14. Stevens, S.S. (1975). Psychophysics. Wiley, New York.Google Scholar

Copyright information

© The Wenner-Gren Center 1988

Authors and Affiliations

  • Andrew Harver
    • 1
  • Donald A. Mahler
  • J. Andrew Daubenspeck
  • Joan F. McGovern
  1. 1.Department of PsychologySUNY Stony BrookStony BrookUSA

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