Abstract
The presence of cholecystokinin (CCK) in extracts of intestine was first described by Ivy and Oldberg (1928), but it was not until 1975 that its occurrence in vertebrate brain was detected (Vanderhaeghen et al., 1975; Dockray, 1976). CCK occurs in brain mainly as the sulphated octapeptide and in the last few years numerous papers have been published on the distribution in the CNS of CCK-containing neurones, although their functional significance remains obscure.
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© 1988 G.N. Woodruff, D.R. Hill, J.A. Kemp, T.M. Shaw, A.R. Crossman and W.C. Graham
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Woodruff, G.N., Hill, D.R., Kemp, J.A., Shaw, T.M., Crossman, A.R., Graham, W.C. (1988). CCK Receptors and Brain Dopaminergic Systems. In: Beart, P.M., Woodruff, G.N., Jackson, D.M. (eds) Pharmacology and Functional Regulation of Dopaminergic Neurons. Satellite Symposia of the IUPHAR 10th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-10047-7_47
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