Endogenous Dopamine Release from Brain Slices: Comparisons with Radiolabelled Release and Regulation by Autoreceptors
The release of dopamine (DA) from nerve terminals in the CNS is known to be influenced by a variety of pharmacological agents, which may have direct effects on some aspect of the release process or act indirectly via ‘presynaptic’ receptors. Such receptors may be for DA itself (‘autoreceptors’) or for other transmitters, and have been proposed to have a physiological role in the regulation of DA release (Chesselet, 1984).
KeywordsAdenylate Cyclase Brain Slice Pertussis Toxin Spontaneous Release Electrical Field Stimulation
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