The Intrinsic Malignancy of Gliomas
Gliomas are a major form of intracranial tumours. They are tumours originating in the neuroglia, i.e. the non-mesenchymal stromal tissue of the central nervous system (CNS). The neuroglial component consists of three cellular elements, namely the astrocytes, the oligodendrocytes and the ependymal cells. The astrocytes and the oligodendrocytes are derived from the migratory spongioblasts of the mantle layer of the neural tube. The spongioblasts in their turn arise from the neural tube epithelium (Figure 1).
KeywordsMetastatic Spread Intracranial Tumour Central Nervous System Tumour Tyrosinase Activity Metastatic Ability
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