Abstract
The disposition of drugs in man covers a wide variety of disparate areas. It includes the absorption, distribution, metabolism and elimination of drugs in or from the body. Absorption of drugs from the gastrointestinal tract is affected by a wide variety of different factors including pH changes, the presence or absence of food, drugs and disease processes [1]. Distribution of drugs throughout the body is also affected by a number of factors such as other drugs and disease processes. However, in this brief review it is not proposed to cover these two major areas of pharmacokinetics. Instead, I will concentrate on the factors which affect drug metabolism and will cover briefly some aspects of drug elimination from the body.
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© 1988 The International Federation of Associations of Pharmaceutical Physicians
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Orme, M. (1988). Geographical, genetic and environmental factors affecting drug disposition. In: Burley, D., Haward, C., Mullinger, B. (eds) The Focus for Pharmaceutical Knowledge. Palgrave, London. https://doi.org/10.1007/978-1-349-09571-1_26
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DOI: https://doi.org/10.1007/978-1-349-09571-1_26
Publisher Name: Palgrave, London
Print ISBN: 978-1-349-09573-5
Online ISBN: 978-1-349-09571-1
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