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New Concepts in Alzheimer’s Disease pp 181–189Cite as

Dissociated Monolayer Cultures of Human Spinal Cord

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Abstract

Recently, we began an investigation on the aetiology of amyotrophic lateral sclerosis (ALS) using neuronal cultures as a tool. Our initial study was done on ‘motoneuron-like’ cells, the ciliary ganglion neurons from the chick embryo (Touzeau and Kato, 1983). Since ALS is a human disease principally affecting spinal motoneurons, it seemed appropriate to develop a culture system for human spinal cord neurons. This paper reports some of the morphological, biochemical and electrophysiological characteristics of these cultures.

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Authors
  1. A. C. Kato
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  2. L. Erkman
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  3. G. Touzeau
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Editor information

Editors and Affiliations

  1. Département de Pharmacologie Biochimique, Centre de Recherche Pierre Fabre, Avenue Jean Moulin 17, 81100, Castres Cédex, France

    M. Briley

  2. Département de Pharmacologie, Centre Médical Universitaire, 1211, Geneva, Switzerland

    A. Kato

  3. Laboratoire de Pharmacologie et de Toxicologie Fondamentales, Route de Narbonne 205, 31400, Toulouse, France

    M. Weber

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© 1986 The Editors and the Contributors

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Kato, A.C., Erkman, L., Touzeau, G. (1986). Dissociated Monolayer Cultures of Human Spinal Cord. In: Briley, M., Kato, A., Weber, M. (eds) New Concepts in Alzheimer’s Disease. Palgrave, London. https://doi.org/10.1007/978-1-349-08639-9_14

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  • DOI: https://doi.org/10.1007/978-1-349-08639-9_14

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-08641-2

  • Online ISBN: 978-1-349-08639-9

  • eBook Packages: MedicineMedicine (R0)

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