Effects of 4-Dimethylaminoazobenzene (DAB) and 4-Cyanodimethylaniline (CDA) in the Mammalian Spot Test

  • J. W. Hart
  • R. Fahrig


In a dose range of 50 to 200 mg/kg, both, DAB and CDA gave inconclusive results in the mammalian spot test. In nearly all cases, the frequency of colour spots was higher in the experimental sets than in the control groups, but with the exception of one experimental set, for CDA, the increases were not statistically significant.


Spot Test Colour Spot Reciprocal Recombination Mitotic Gene Conversion Mother Animal 
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Copyright information

© United Kingdom Environmental Mutagen Society 1985

Authors and Affiliations

  • J. W. Hart
    • 1
    • 3
  • R. Fahrig
    • 2
  1. 1.Leo Pharmaceutical Products LtdBallerupDenmark
  2. 2.Fraunhofer-Institut für Toxikologie Und AerosolferschungGermany
  3. 3.National Agency of Environmental ProtectionCopenhagenDenmark

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