Abstract
Over the past few years, it has become increasingly evident that the endocrine state, particularly with respect to circulating levels of estrogen, can significantly effect the behavioral response of both humans (Bedard et al. 1979; Nausieda et al. 1979a; Villeneuve et al. 1980) and animals (Bedard et al. 1978; Chiodo et al. 1979, 1981; Gordon et al. 1980; Hruska and Silbergeld 1980; Koller et al. 1980; Niak et al. 1978; Nausieda et al. 1979b; Gordon, 1980) to dopamine (DA)-related drugs. For example, estrogen has been reported to reduce dyskinesias associated with chronic neuroleptic therapy or with L-Dopa administration in humans (Villeneuve et al. 1980; Glazer et al. 1983, 1984), disorders which are thought to be related to a hyperf unctioning of extrapyramidal DA systems.
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Chiodo, L.A., Glazer, W.M., Bunney, B.S. (1986). Midbrain Dopamine Neurons: Electrophysiological Studies on the Acute Effects of Estrogen. In: Woodruff, G.N., Poat, J.A., Roberts, P.J. (eds) Dopaminergic Systems and their Regulation. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07431-0_21
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DOI: https://doi.org/10.1007/978-1-349-07431-0_21
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