Calcium Phosphate Bioceramics

  • K. de Groot
Part of the Strathclyde Bioengineering Seminars book series (KESE)


Since Dreesman applied calcium sulphate (plaster of Paris) as a bone substitute in the last century (1894), interest in ceramics consisting of physiological salts has been increasing to a point where they are clinically applied in a growing number of surgical disciplines. Several review articles have appeared recently (de Groot, 1981; Jarcho, 1981) and it suffices therefore to mention that the two calcium phosphate minerals apatite and 8-whitlockite have been studied most.


Compressive Strength Calcium Phosphate Neighbour Lymph Node Fatigue Failure Bone Substitute 
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  1. Davidge, R.W. (1979). Mechanical Behaviour of Ceramics, Cambridge University Press, Cambridge.Google Scholar
  2. Driessen, A.A., Klein, C.P.A.T. and de Groot, K. (1982). Preparation and some properties of sintered R-whitlockite. Biomaterials, 3, 113–117.CrossRefPubMedGoogle Scholar
  3. de Groot, K. (1981). Degradable ceramics, in D.F. Williams (ed.), Biocompatibility of Clinical Implant Materials, vol.1, CRC Press, Boca Raton, Florida, pp.199–224.Google Scholar
  4. de Groot, K. (1983). Ceramics based on calciumphosphates, in P. Vincenzini (ed.), Ceramics in Surgery, Elsevier, Amsterdam, pp.79–90.Google Scholar
  5. de Groot, K., de Putter, C., Sillevis Smitt, P.A.E. and Driessen, A.A. (1981). Mechanical failure of artificial teeth made of dense hydroxylapatite. Sci.Ceram., 11, 433–439.Google Scholar
  6. Jarcho, M. (1981). Calcium phosphate ceramics as hard tissue prosthetics. Clin.Orthop.Relat.Res., 157, 259–278.PubMedGoogle Scholar
  7. Kingery, W.D. (1960). Introduction to Ceramics, John Wiley and Sons, New York, p.621.Google Scholar
  8. Klawitter, J.J. (1970). A Basic Investigation of Bone Growth into a Porous Material, PhD.Thesis, Clemson University, South Carolina.Google Scholar
  9. Klein, C.P.A.T., de Groot, K. and Driessen, A.A. (1983). Biodegradation of calcium phosphate ceramics, in P. Vincenzini (ed.), Ceramics in Surgery, Elsevier, Amsterdam, pp.105–115.Google Scholar
  10. Koster, K, Heide, H. and Konig, R. (1977). Resorbierbare Calciumphospatkeramik im Tierexperimenten unter Belastung. Langenbecks Arch.Chir., 343, 173–177.CrossRefPubMedGoogle Scholar
  11. Peelen, J.G.J., Rejda, B.V., Vermeiden, J.P.W. and de Groot, K. (1977). Sintered tricalciumphosphate as bioceramic. Sci.Ceram., 9, 226–232.Google Scholar
  12. de Putter, C., de Groot, K. and Sillevis Smitt, P.A.E. (1983). Permucosal application of implants of dense hydroxylapatite in prosthetic dentistry, in P. Vincenzini (ed.), Ceramics in Surgery, Elsevier, Amsterdam, pp.395–402.Google Scholar
  13. Ritter, J.E. (1974). Engineering design and failure of brittle materials, in R.C. Bradt, D. Hasselman, (eds.), Fracture Mechanics of Ceramics, Vol.2, Plenum Press, New York, pp.667–686.Google Scholar
  14. Rootare, H.M. and Graig, R.G. (1974). Characterization of the compaction and sintering of hydroxyapatite powders by mercury porosimetry. Powder Technol., 9, 199–203.CrossRefGoogle Scholar
  15. Ryshkewitch, E. (1953). Compression strength of porous sintered alumina and zirconia. J.Am.Ceram.Soc., 36, 65–72.CrossRefGoogle Scholar
  16. Swart, J.G.N. and de Groot, K. (1980). Clinical experiences with sintered calciumphosphate as oral implant material, in G. Heimke (ed.), Dental Implants, Carl Hanser Verlag, Munich, pp.97–103.Google Scholar
  17. de With, G., van Dijk, H.J.A., Hattu, N. and Prijs, K. (1981). Preparation, microstructure and mechanical properties of dense polycrystalline hydroxyapatite. J.Mater.Sci., 16, 1592–1595.CrossRefGoogle Scholar
  18. van der Zel, J.M. and de Groot, K. (1981). Dutch patent. Implant of ceramic material, 82200412.3.Google Scholar

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© Bioengineering Unit, University of Strathclyde 1984

Authors and Affiliations

  • K. de Groot

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