Abstract
Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterised by elevated levels of low density lipoprotein cholesterol (LDL-C), tendon xanthomas and premature coronary atherosclerosis (Mabuchi et al., 1983). This abnormality is inherited as an incompletely dominant strain, resulting in a deficiency of cell surface receptors and defective binding of low density lipoprotein (LDL) to these receptors (Goldstein et al., 1975).
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© 1984 Bioengineering Unit, University of Strathclyde
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Lotan, N. et al. (1984). Agarose-Based Haemoperfusion Columns For The Removal Of Excess Ldl-cholesterol From Whole Blood. In: Paul, J.P., Gaylor, J.D.S., Courtney, J.M., Gilchrist, T. (eds) Biomaterials in Artificial Organs. Strathclyde Bioengineering Seminars. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07283-5_22
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DOI: https://doi.org/10.1007/978-1-349-07283-5_22
Publisher Name: Palgrave Macmillan, London
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